4.3 Article

New oral liposomal vitamin C formulation: properties and bioavailability

期刊

JOURNAL OF LIPOSOME RESEARCH
卷 30, 期 3, 页码 227-234

出版社

TAYLOR & FRANCIS LTD
DOI: 10.1080/08982104.2019.1630642

关键词

Liposome; vitamin C; efficacy; bioavailability; stability

资金

  1. National Centre for Research and Development [UOD-DEM-1-027/001]

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Vitamin C is the exogenous compound necessary for a variety of metabolic processes; therefore, the efficient delivery is critical for the maintenance of body homeostasis. Vitamin C pharmacokinetics and low quantities in processed foodstuff, necessitates its continuous supplementation. In the paper, we present the new liposomal formulation of vitamin C free of harmful organic solvents. The formulation was quantitatively characterized with respect to its chemically composition and nano-structuring. The vitamin C accessibility to cells from the formulation was evaluated using evidence derived from experiments performed on cell cultures. Finally, the enhanced bioavailability of vitamin C from the formulation was demonstrated in the medical experiment.

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