期刊
JOURNAL OF LIPOSOME RESEARCH
卷 30, 期 3, 页码 227-234出版社
TAYLOR & FRANCIS LTD
DOI: 10.1080/08982104.2019.1630642
关键词
Liposome; vitamin C; efficacy; bioavailability; stability
资金
- National Centre for Research and Development [UOD-DEM-1-027/001]
Vitamin C is the exogenous compound necessary for a variety of metabolic processes; therefore, the efficient delivery is critical for the maintenance of body homeostasis. Vitamin C pharmacokinetics and low quantities in processed foodstuff, necessitates its continuous supplementation. In the paper, we present the new liposomal formulation of vitamin C free of harmful organic solvents. The formulation was quantitatively characterized with respect to its chemically composition and nano-structuring. The vitamin C accessibility to cells from the formulation was evaluated using evidence derived from experiments performed on cell cultures. Finally, the enhanced bioavailability of vitamin C from the formulation was demonstrated in the medical experiment.
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