期刊
APPLIED RADIATION AND ISOTOPES
卷 118, 期 -, 页码 350-353出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.apradiso.2016.10.010
关键词
Zirconium-89; Zr-89; Zr-89; Ti-44; Spot welding; Cyclotron solid targetry
类别
资金
- NIH Radiological Sciences Training Grant [T32-CA009206]
- Michael Phelps Family Foundation
Zirconium-89 finds broad application for use in positron emission tomography. Its cyclotron production has been limited by the heat transfer from yttrium targets at high beam currents. A spot welding technique allows a three-fold increase in beam current, without affecting Zr-89 quality. An yttrium foil, welded to a jet-cooled tantalum support base accommodates a 50 A proton beam degraded to 14 MeV. The resulting activity yield of 48 4 MBq/(mu A.hr) now extends the outreach of Zr-89 for a broader distribution.
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