期刊
JOURNAL OF EXPOSURE SCIENCE AND ENVIRONMENTAL EPIDEMIOLOGY
卷 30, 期 4, 页码 596-605出版社
SPRINGERNATURE
DOI: 10.1038/s41370-019-0150-5
关键词
Black carbon; Peri-urban; Personal exposure; Exposure modeling; PM2; 5; India
Scalable exposure assessment approaches that capture personal exposure to particles for purposes of epidemiology are currently limited, but valuable, particularly in low-/middle-income countries where sources of personal exposure are often distinct from those of ambient concentrations. We measured 2 x 24-h integrated personal exposure to PM(2.5)and black carbon in two seasons in 402 participants living in peri-urban South India. Means (sd) of PM(2.5)personal exposure were 55.1(82.8) mu g/m(3)for men and 58.5(58.8) mu g/m(3)for women; corresponding figures for black carbon were 4.6(7.0) mu g/m(3)and 6.1(9.6) mu g/m(3). Most variability in personal exposure was within participant (intra-class correlation ~20%). Personal exposure measurements were not correlated (R-spearman < 0.2) with annual ambient concentration at residence modeled by land-use regression; no subgroup with moderate or good agreement could be identified (weighted kappa <= 0.3 in all subgroups). We developed models to predict personal exposure in men and women separately, based on time-invariant characteristics collected at baseline (individual, household, and general time-activity) using forward stepwise model building with mixed models. Models for women included cooking activities and household socio-economic position, while models for men included smoking and occupation. Models performed moderately in terms of between-participant variance explained (38-53%) and correlations between predictions and measurements (R-spearman: 0.30-0.50). More detailed, time-varying time-activity data did not substantially improve the performance of the models. Our results demonstrate the feasibility of predicting personal exposure in support of epidemiological studies investigating long-term particulate matter exposure in settings characterized by solid fuel use and high occupational exposure to particles.
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