期刊
JOURNAL OF EXPERIMENTAL BOTANY
卷 70, 期 16, 页码 4267-4277出版社
OXFORD UNIV PRESS
DOI: 10.1093/jxb/erz292
关键词
Casparian strip integrity factor; LRR-RLK; phytosulfokine; plant peptide containing sulfated tyrosine; root meristem growth factor; sulfated peptide hormone; tyrosine sulfation; tyrosylprotein sulfotransferase
资金
- Deutsche Forschungsgemeinschaft [SA495/13-2]
Sulfated peptides are plant hormones that are active at nanomolar concentrations. The sulfation at one or more tyrosine residues is catalysed by tyrosylprotein sulfotransferase (TPST), which is encoded by a single-copy gene. The sulfate group is provided by the co-substrate 3-phosphoadenosine 5 '-phosphosulfate (PAPS), which links synthesis of sulfated signaling peptides to sulfur metabolism. The precursor proteins share a conserved DY-motif that is implicated in specifying tyrosine sulfation. Several sulfated peptides undergo additional modification such as hydroxylation of proline and glycosylation of hydroxyproline. The modifications render the secreted signaling molecules active and stable. Several sulfated signaling peptides have been shown to be perceived by leucine-rich repeat receptor-like kinases (LRR-RLKs) but have signaling pathways that, for the most part, are yet to be elucidated. Sulfated peptide hormones regulate growth and a wide variety of developmental processes, and intricately modulate immunity to pathogens. While basic research on sulfated peptides has made steady progress, their potential in agricultural and pharmaceutical applications has yet to be explored. Signaling peptides are ubiquitous in higher plants and regulate growth, development, and environmental interactions. Sulfation provides a specific modification that is catalysed by an enzyme unique to these secreted signals.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据