相关参考文献
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Rebecca L. Siegel et al.
CA-A CANCER JOURNAL FOR CLINICIANS (2018)
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ONCOTARGET (2017)
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M. Aggarwal et al.
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ACTA BIOCHIMICA ET BIOPHYSICA SINICA (2014)
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CANCER CELL (2014)
Degradation of mutant p53H175 protein by Zn(II) through autophagy
A. Garufi et al.
CELL DEATH & DISEASE (2014)
Mutational landscape and significance across 12 major cancer types
Cyriac Kandoth et al.
NATURE (2013)
Initiation of prostate cancer in mice by Tp53R270H: evidence for an alternative molecular progression
Ruth L. Vinall et al.
DISEASE MODELS & MECHANISMS (2012)
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William A. Freed-Pastor et al.
GENES & DEVELOPMENT (2012)
Targeting p53 in Vivo: A First-in-Human Study With p53-Targeting Compound APR-246 in Refractory Hematologic Malignancies and Prostate Cancer
Soren Lehmann et al.
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The mutational landscape of lethal castration-resistant prostate cancer
Catherine S. Grasso et al.
NATURE (2012)
Selective Depletion of Mutant p53 by Cancer Chemopreventive Isothiocyanates and Their Structure-Activity Relationships
Xiantao Wang et al.
JOURNAL OF MEDICINAL CHEMISTRY (2011)
Phenethyl isothiocyanate sensitizes human cervical cancer cells to apoptosis induced by cisplatin
Xiantao Wang et al.
MOLECULAR NUTRITION & FOOD RESEARCH (2011)
Endogenously induced DNA double strand breaks arise in heterochromatic DNA regions and require ataxia telangiectasia mutated and Artemis for their repair
Lisa Woodbine et al.
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Phenethyl Isothiocyanate Inhibits Oxidative Phosphorylation to Trigger Reactive Oxygen Species-mediated Death of Human Prostate Cancer Cells
Dong Xiao et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
A common gain of function of p53 cancer mutants in inducing genetic instability
D. P. Liu et al.
ONCOGENE (2010)
Nutrient isothiocyanates covalently modify and inhibit the inflammatory cytokine macrophage migration inhibitory factor (MIF)
Janet V. Cross et al.
BIOCHEMICAL JOURNAL (2009)
A New Class of Isothiocyanate-Based Irreversible Inhibitors of Macrophage Migration Inhibitory Factor
Hajer Ouertatani-Sakouhi et al.
BIOCHEMISTRY (2009)
Mutant p53 Drives Invasion by Promoting Integrin Recycling
Patricia A. J. Muller et al.
CELL (2009)
The p53 Family Protein p73 Provides New Insights into Cancer Chemosensitivity and Targeting
Paolo Lunghi et al.
CLINICAL CANCER RESEARCH (2009)
Direct Modification of the Proinflammatory Cytokine Macrophage Migration Inhibitory Factor by Dietary Isothiocyanates
Kristin K. Brown et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Covalent binding to tubulin by isothiocyanates - A mechanism of cell growth arrest and apoptosis
Lixin Mi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Transcriptional control of human p53-regulated genes
Todd Riley et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2008)
Role of Reactive Oxygen Intermediates in Cellular Responses to Dietary Cancer Chemoprevention Agents
Jedrzej Antosiewicz et al.
PLANTA MEDICA (2008)
The role of protein binding in induction of apoptosis by phenethyl isothiocyanate and sulforaphane in human non-small lung cancer cells
Lixin Mi et al.
CANCER RESEARCH (2007)
P53 gain-of-function cancer mutants induce genetic instability by inactivating ATM
Hoseok Song et al.
NATURE CELL BIOLOGY (2007)
Are interactions with p63 and p73 involved in mutant p53 gain of oncogenic function?
Y. Li et al.
ONCOGENE (2007)
Mutant p53: an oncogenic transcription factor
S. Strano et al.
ONCOGENE (2007)
Restoration of p53 function leads to tumour regression in vivo
Andrea Ventura et al.
NATURE (2007)
Phenethyl isothiocyanate-induced apoptosis in PC-3 human prostate cancer cells is mediated by reactive oxygen species-dependent disruption of the mitochondrial membrane potential
Dong Xiao et al.
CARCINOGENESIS (2006)
Gain of function of mutant p53: The mutant p53/NF-Y protein complex reveals an aberrant transcriptional mechanism of cell cycle regulation
Silvia Di Agostino et al.
CANCER CELL (2006)
Selective killing of oncogenically transformed cells through a ROS-mediated mechanism by β-phenylethyl isothiocyanate
Dunyaporn Trachootham et al.
CANCER CELL (2006)
Isothiocyanates as cancer chemopreventive agents: Their biological activities and metabolism in rodents and humans
CC Conaway et al.
CURRENT DRUG METABOLISM (2002)
Restoration of the tumor suppressor function to mutant p53 by a low-molecular-weight compound
VJN Bykov et al.
NATURE MEDICINE (2002)
Phytochemicals from cruciferous plants protect against cancer by modulating carcinogen metabolism
P Talalay et al.
JOURNAL OF NUTRITION (2001)
Mutations within the tumour suppressor gene p53 are not confined to a late event in prostate cancer progression: a review of the evidence
SR Downing et al.
UROLOGIC ONCOLOGY (2001)
A subset of tumor-derived mutant forms of p53 down-regulate p63 and p73 through a direct interaction with the p53 core domain
C Gaiddon et al.
MOLECULAR AND CELLULAR BIOLOGY (2001)
High metastatic potential in mice inheriting a targeted p53 missense mutation
G Liu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
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