期刊
JOURNAL OF DERMATOLOGY
卷 46, 期 10, 页码 902-906出版社
WILEY
DOI: 10.1111/1346-8138.15022
关键词
alcohol drinking; epidemiology; lifestyle; varicose veins; venous thromboembolism
类别
资金
- Ministry of Education, Culture, Sports, Science and Technology [16K19723]
- Grants-in-Aid for Scientific Research [16K19723] Funding Source: KAKEN
The effect of alcohol intake on varicose veins (VV) has not been determined by its consumption level. The aim of this study was to investigate the association between alcohol intake and VV in an elderly general population. Using a cross-sectional approach, the Shimane CoHRE Study data, comprising a total of 1060 participants, were analyzed. By multivariate regression analysis adjusted with basic characteristics, past work history, lifestyle-related factors and medical history, compared with non-drinkers, mild drinkers (<20.0 g/day) showed a significantly lower adjusted odds ratio (aOR) of VV (aOR = 0.64, P = 0.036). In a similar way, regular drinkers (1-5 days/week) showed a significantly lower aOR of VV when compared with occasional drinkers (aOR = 0.57, P = 0.032). VV and alcohol intake showed J-curve relationships. In a stratified analysis by alcohol consumption levels, the association of smoking and VV were also observed in moderate to heavy drinkers and habitual drinkers. These findings can provide better understanding of pathophysiological mechanism and be used for evidence-based patient education.
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