期刊
APPLIED PHYSIOLOGY NUTRITION AND METABOLISM
卷 41, 期 9, 页码 1005-1007出版社
CANADIAN SCIENCE PUBLISHING, NRC RESEARCH PRESS
DOI: 10.1139/apnm-2016-0178
关键词
cerebellum; Vastus medialis muscle; bioenergetics; homocysteine
资金
- Serbian Ministry of Education, Science, and Technological Development [175037]
- Faculty of Sport and Physical Education, University of Novi Sad
- Center for Health, Exercise, and Sports Sciences, Belgrade [16-07-15]
In this randomized, double-blind, crossover trial, we evaluated whether 4-week supplementation with guanidinoacetic acid (GAA) is superior to creatine in facilitating creatine levels in healthy men (n = 5). GAA (3.0 g/day) resulted in a more powerful rise (up to 16.2%) in tissue creatine levels in vastus medialis muscle, middle-cerebellar peduncle, and paracentral grey matter, as compared with creatine (P < 0.05). These results indicate that GAA as a preferred alternative to creatine for improved bioenergetics in energy-demanding tissues.
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