期刊
JOURNAL OF COORDINATION CHEMISTRY
卷 72, 期 12, 页码 2091-2105出版社
TAYLOR & FRANCIS LTD
DOI: 10.1080/00958972.2019.1629430
关键词
Gold(III); spectral analysis; antimicrobial activity; cytotoxicity; antioxidant activity
资金
- Trakya University [TUBAP-2010/72]
- Trakya University
In the present study, the reactions involving caffeine (CA) and gold(III) were investigated. The synthesized complex was characterized by using mass, UV-visible, FTIR, H-1 and C-13 NMR, and TG-DTA analyses. From these analyses, it is predicted that the complex has the formula [Au(CA)(2)(Cl)(2)]Cl. In addition, antimicrobial, cytotoxicity, and antioxidant activities of the obtained complex were investigated. Investigation of antimicrobial properties demonstrated that the complex has important antibacterial and antifungal activities. The cytotoxic activity of the complex showed potent cytotoxicity against growth of human prostate (Du145), cervix (HeLa), colon (HT29), and breast (MCF7) cancer cells. Additionally, the complex showed significant antioxidant activity.
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