期刊
JOURNAL OF CLINICAL NEUROSCIENCE
卷 68, 期 -, 页码 97-100出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.jocn.2019.07.027
关键词
Essential tremor; Ventralis intermediate nucleus; Functional neurosurgery
资金
- Norman Collisson Foundation, Oxford NIHR BRC, UK Charles Wolfson Charitable Trust
Indirect targeting of the Ventralis Intermedius Nucleus (Vim) is widely used for functional neurosurgical procedures to treat essential tremor (ET). Here, we review if the laterality of the Vim depends on the diameter of the third ventricle and if a targeting approach that incorporates this correlation can facilitate targeting and yields accurate lead placement. We analyzed 15 consecutive ET patients. Vim targeting was adapted according to the width of the third ventricle and the lateral distance to the internal capsule (IC). Postoperative outcome was assessed 12 months post-OP based on the Bain-Findley score. Application of this targeting approach resulted in mean target coordinates of LAT 12.8 +/- 1.5; AP -3.6 +/- 1.0 and VERT 0 +/- 0 mm and which projected onto the Vim. The laterality of IC and Vim are correlated to the width of the third ventricle. The mean postoperative tremor reduction was 63.0%. In summary, adjusting the lateral coordinate according to the width of the third ventricle leads to accurate targeting and effective tremor reduction. (C) 2019 Elsevier Ltd. All rights reserved.
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