期刊
JOURNAL OF ANTIBIOTICS
卷 72, 期 10, 页码 736-743出版社
NATURE PUBLISHING GROUP
DOI: 10.1038/s41429-019-0203-y
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资金
- Liaoning Province Fund for Nature [01032017001]
- Shenyang Agricultural University Postdoctoral Fund [770215012]
- Shenyang Agricultural University Introducing Talent Fund [880415016]
Two novel depsipeptides xenematides F and G (1, 2), were isolated from entomopathogenic Xenorhabdus budapestensis SN84 along with a known compound xenematide B. The structures of the two new molecules were elucidated using NMR, MS and Marfey's method. The xenematide G (2) contains alpha-aminoheptanoic acid, a non-protein amino acid that is rarely found in secondary metabolites from entomopathogenic bacteria. Xenematides F and G were tested for antibacterial activity. Xenematide G (2) exhibited moderate antibacterial activity.
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