相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Effects of phosphorylation on the NLRP3 inflammasome
Christina F. Sandall et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2019)
MCC950 directly targets the NLRP3 ATP- hydrolysis motif for inflammasome inhibition
Rebecca C. Coll et al.
NATURE CHEMICAL BIOLOGY (2019)
MCC950 closes the active conformation of NLRP3 to an inactive state
Ana Tapia-Abelian et al.
NATURE CHEMICAL BIOLOGY (2019)
AT-533, a Hsp90 inhibitor, attenuates HSV-1-induced inflammation
Feng Li et al.
BIOCHEMICAL PHARMACOLOGY (2019)
Candidalysin Crucially Contributes to Nlrp3 Inflammasome Activation by Candida albicans Hyphae
Ona Rogiers et al.
MBIO (2019)
A multicomponent toxin from Bacillus cereus incites inflammation and shapes host outcome via the NLRP3 inflammasome
Anukriti Mathur et al.
NATURE MICROBIOLOGY (2019)
Cutting Edge: Mitochondrial Assembly of the NLRP3 Inflammasome Complex Is Initiated at Priming
Eric I. Elliott et al.
JOURNAL OF IMMUNOLOGY (2018)
Induction of NLRP3 Inflammasome Activation by Heme in Human Endothelial Cells
Judit Erdei et al.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2018)
Macrophage migration inhibitory factor is required for NLRP3 inflammasome activation
Tali Lang et al.
NATURE COMMUNICATIONS (2018)
The E3 ubiquitin ligase Pellino2 mediates priming of the NLRP3 inflammasome
Fiachra Humphries et al.
NATURE COMMUNICATIONS (2018)
The oxidized phospholipid oxPAPC protects from septic shock by targeting the non-canonical inflammasome in macrophages
Lan H. Chu et al.
NATURE COMMUNICATIONS (2018)
Hsp90 inhibition as a means to inhibit activation of the NLRP3 inflammasome
Niina Piippo et al.
SCIENTIFIC REPORTS (2018)
USP7 and USP47 deubiquitinases regulate NLRP3 inflammasome activation
Pablo Palazon-Riquelme et al.
EMBO REPORTS (2018)
New mitochondrial DNA synthesis enables NLRP3 inflammasome activation
Zhenyu Zhong et al.
NATURE (2018)
Chloride regulates dynamic NLRP3-dependent ASC oligomerization and inflammasome priming
Jack P. Green et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)
SUMO-mediated regulation of NLRP3 modulates inflammasome activity
Rachael Barry et al.
NATURE COMMUNICATIONS (2018)
PtdIns4P on dispersed trans-Golgi network mediates NLRP3 inflammasome activation
Jueqi Chen et al.
NATURE (2018)
NLRP3 lacking the leucine-rich repeat domain can be fully activated via the canonical inflammasome pathway
Iva Hafner-Bratkovic et al.
NATURE COMMUNICATIONS (2018)
The fungal peptide toxin Candidalysin activates the NLRP3 inflammasome and causes cytolysis in mononuclear phagocytes
Lydia Kasper et al.
NATURE COMMUNICATIONS (2018)
Inhibition of Heat Shock Protein 90 by 17-AAG Reduces Inflammation via P2X7 Receptor/NLRP3 Inflammasome Pathway and Increases Neurogenesis After Subarachnoid Hemorrhage in Mice
Yuchun Zuo et al.
FRONTIERS IN MOLECULAR NEUROSCIENCE (2018)
Guanylate binding proteins facilitate caspase-11-dependent pyroptosis in response to type 3 secretion system-negative Pseudomonas aeruginosa
Arjun Balakrishnan et al.
CELL DEATH DISCOVERY (2018)
Post-translational regulation of inflammasomes
Jie Yang et al.
CELLULAR & MOLECULAR IMMUNOLOGY (2017)
PKR induces the expression of NLRP3 by regulating the NF-κB pathway in Porphyromonas gingivalis-infected osteoblasts
Kaya Yoshida et al.
EXPERIMENTAL CELL RESEARCH (2017)
The intracellular chloride channel proteins CLIC1 and CLIC4 induce IL-1β transcription and activate the NLRP3 inflammasome
Raquel Domingo-Fernandez et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2017)
NLRP3 inflammasome assembly is regulated by phosphorylation of the pyrin domain
Andrea Stutz et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2017)
Protein kinase D at the Golgi controls NLRP3 inflammasome activation
Zhirong Zhang et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2017)
ARIH2 Ubiquitinates NLRP3 and Negatively Regulates NLRP3 Inflammasome Activation in Macrophages
Akira Kawashima et al.
JOURNAL OF IMMUNOLOGY (2017)
NLRP3 Phosphorylation Is an Essential Priming Event for Inflammasome Activation
Nan Song et al.
MOLECULAR CELL (2017)
NADPH Oxidase 2 Regulates NLRP3 Inflammasome Activation in the Brain after Traumatic Brain Injury
Merry W. Ma et al.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2017)
MARK4 regulates NLRP3 positioning and inflammasome activation through a microtubule-dependent mechanism
Xuan Li et al.
NATURE COMMUNICATIONS (2017)
CLICs-dependent chloride efflux is an essential and proximal upstream event for NLRP3 inflammasome activation
Tiantian Tang et al.
NATURE COMMUNICATIONS (2017)
Boron-Based Inhibitors of the NLRP3 Inflammasome
Alex G. Baldwin et al.
CELL CHEMICAL BIOLOGY (2017)
Shiga Toxins Activate the NLRP3 Inflammasome Pathway To Promote Both Production of the Proinflammatory Cytokine Interleukin-1 beta and Apoptotic Cell Death
Moo-Seung Lee et al.
INFECTION AND IMMUNITY (2016)
A Genome-wide CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) Screen Identifies NEK7 as an Essential Component of NLRP3 Inflammasome Activation
Jonathan L. Schmid-Burgk et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2016)
NLRP3 activation and mitosis are mutually exclusive events coordinated by NEK7, a new inflammasome component
Hexin Shi et al.
NATURE IMMUNOLOGY (2016)
Corosolic acid ameliorates acute inflammation through inhibition of IRAK-1 phosphorylation in macrophages
Seung-Jae Kim et al.
BMB REPORTS (2016)
IRGB10 Liberates Bacterial Ligands for Sensing by the AIM2 and Caspase-11-NLRP3 Inflammasomes
Si Ming Man et al.
CELL (2016)
Bile Acids Control Inflammation and Metabolic Disorder through Inhibition of NLRP3 Inflammasome
Chuansheng Guo et al.
IMMUNITY (2016)
K+ Efflux-Independent NLRP3 Inflammasome Activation by Small Molecules Targeting Mitochondria
Christina J. Gross et al.
IMMUNITY (2016)
Human Monocytes Engage an Alternative Inflammasome Pathway
Moritz M. Gaidt et al.
IMMUNITY (2016)
The cell biology of inflammasomes: Mechanisms of inflammasome activation and regulation
Deepika Sharma et al.
JOURNAL OF CELL BIOLOGY (2016)
NLRP3 tyrosine phosphorylation is controlled by protein tyrosine phosphatase PTPN22
Marianne R. Spalinger et al.
JOURNAL OF CLINICAL INVESTIGATION (2016)
NEK7 is an essential mediator of NLRP3 activation downstream of potassium efflux
Yuan He et al.
NATURE (2016)
NLRP3 inflammasome inhibition is disrupted in a group of auto-inflammatory disease CAPS mutations
Leanne Mortimer et al.
NATURE IMMUNOLOGY (2016)
NOX4-dependent fatty acid oxidation promotes NLRP3 inflammasome activation in macrophages
Jong-Seok Moon et al.
NATURE MEDICINE (2016)
The E3 ubiquitin ligase TRIM31 attenuates NLRP3 inflammasome activation by promoting proteasomal degradation of NLRP3
Hui Song et al.
NATURE COMMUNICATIONS (2016)
Fenamate NSAIDs inhibit the NLRP3 inflammasome and protect against Alzheimer's disease in rodent models
Michael J. D. Daniels et al.
NATURE COMMUNICATIONS (2016)
FADD regulates NF-κB activation and promotes ubiquitination of cFLIPL to induce apoptosis
Kishu Ranjan et al.
SCIENTIFIC REPORTS (2016)
Disruption of glycolytic flux is a signal for inflammasome signaling and pyroptotic cell death
Laura E. Sanman et al.
ELIFE (2016)
Dopamine Controls Systemic Inflammation through Inhibition of NLRP3 Inflammasome
Yiqing Yan et al.
CELL (2015)
Gasdermin D is an executor of pyroptosis and required for interleukin-1β secretion
Wan-ting He et al.
CELL RESEARCH (2015)
Caspase-11 activates a canonical NLRP3 inflammasome by promoting K+ efflux
Sebastian Ruehl et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2015)
Caspase-4 mediates non-canonical activation of the NLRP3 inflammasome in human myeloid cells
Jonathan L. Schmid-Burgk et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2015)
NLRP3 inflammasome activation downstream of cytoplasmic LPS recognition by both caspase-4 and caspase-5
Paul J. Baker et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2015)
Caspase-11 Requires the Pannexin-1 Channel and the Purinergic P2X7 Pore to Mediate Pyroptosis and Endotoxic Shock
Dahai Yang et al.
IMMUNITY (2015)
Lipopolysaccharide Primes the NALP3 Inflammasome by Inhibiting Its Ubiquitination and Degradation Mediated by the SCFFBXL2 E3 Ligase
SeungHye Han et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2015)
MAVS Promotes Inflammasome Activation by Targeting ASC for K63-Linked Ubiquitination via the E3 Ligase TRAF3
Kai Guan et al.
JOURNAL OF IMMUNOLOGY (2015)
Bacterial RNA: An Underestimated Stimulus for Innate Immune Responses
Tatjana Eigenbrod et al.
JOURNAL OF IMMUNOLOGY (2015)
K+ Efflux Agonists Induce NLRP3 Inflammasome Activation Independently of Ca2+ Signaling
Michael A. Katsnelson et al.
JOURNAL OF IMMUNOLOGY (2015)
Multiple Cathepsins Promote Pro-IL-1β Synthesis and NLRP3-Mediated IL-1β Activation
Gregory M. Orlowski et al.
JOURNAL OF IMMUNOLOGY (2015)
Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling
Nobuhiko Kayagaki et al.
NATURE (2015)
Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death
Jianjin Shi et al.
NATURE (2015)
The transcription factor IRF1 and guanylate-binding proteins target activation of the AIM2 inflammasome by Francisella infection
Si Ming Man et al.
NATURE IMMUNOLOGY (2015)
Guanylate-binding proteins promote activation of the AIM2 inflammasome during infection with Francisella novicida
Etienne Meunier et al.
NATURE IMMUNOLOGY (2015)
A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases
Rebecca C. Coll et al.
NATURE MEDICINE (2015)
Inflammasomes: mechanism of action, role in disease, and therapeutics
Haitao Guo et al.
NATURE MEDICINE (2015)
Bacterial exotoxins and the inflammasome
Allison J. Greaney et al.
FRONTIERS IN IMMUNOLOGY (2015)
The P2X7 receptor: Shifting from a low- to a high-conductance channel - An enigmatic phenomenon?
Luiz Anastacio Alves et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2014)
Mechanisms and Functions of Inflammasomes
Mohamed Lamkanfi et al.
CELL (2014)
Mitochondrial apoptosis is dispensable for NLRP3 inflammasome activation but non-apoptotic caspase-8 is required for inflammasome priming
Ramanjaneyulu Allam et al.
EMBO REPORTS (2014)
Lysosomes Integrate Metabolic-Inflammatory Cross-talk in Primary Macrophage Inflammasome Activation
Kassandra Weber et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
RNA and β-Hemolysin of Group B Streptococcus Induce Interleukin-1β ( IL-1β) by Activating NLRP3 Inflammasomes in Mouse Macrophages*
Rahul Gupta et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
Cytosolic Double-Stranded RNA Activates the NLRP3 Inflammasome via MAVS-Induced Membrane Permeabilization and K+ Efflux
Luigi Franchi et al.
JOURNAL OF IMMUNOLOGY (2014)
FADD and Caspase-8 Mediate Priming and Activation of the Canonical and Noncanonical Nlrp3 Inflammasomes
Prajwal Gurung et al.
JOURNAL OF IMMUNOLOGY (2014)
Inflammatory caspases are innate immune receptors for intracellular LPS
Jianjin Shi et al.
NATURE (2014)
Caspase-11 activation requires lysis of pathogen-containing vacuoles by IFN-induced GTPases
Etienne Meunier et al.
NATURE (2014)
IRAK-1 bypasses priming and directly links TLRs to rapid NLRP3 inflammasome activation
Keng-Mean Lin et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Human NLRP3 inflammasome senses multiple types of bacterial RNAs
Wenwen Sha et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Rift Valley fever virus infection induces activation of the NLRP3 inflammasome
Megan E. Ermler et al.
VIROLOGY (2014)
ADP-Ribosylation of NLRP3 by Mycoplasma pneumoniae CARDS Toxin Regulates Inflammasome Activity
Santanu Bose et al.
MBIO (2014)
The Adaptor MAVS Promotes NLRP3 Mitochondrial Localization and Inflammasome Activation
Naeha Subramanian et al.
CELL (2013)
Nitric oxide suppresses NLRP3 inflammasome activation and protects against LPS-induced septic shock
Kairui Mao et al.
CELL RESEARCH (2013)
The protein kinase PKR is critical for LPS-induced iNOS production but dispensable for inflammasome activation in macrophages
Yuan He et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2013)
Human astrocytes express a novel NLRP2 inflammasome
Julia Minkiewicz et al.
GLIA (2013)
Mitochondrial Cardiolipin Is Required for Nlrp3 Inflammasome Activation
Shankar S. Iyer et al.
IMMUNITY (2013)
K+ Efflux Is the Common Trigger of NLRP3 Inflammasome Activation by Bacterial Toxins and Particulate Matter
Raul Munoz-Planillo et al.
IMMUNITY (2013)
Deubiquitinases Regulate the Activity of Caspase-1 and Interleukin-1β Secretion via Assembly of the Inflammasome
Gloria Lopez-Castejon et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
TLR Agonists Stimulate Nlrp3-Dependent IL-1β Production Independently of the Purinergic P2X7 Receptor in Dendritic Cells and In Vivo
Yuan He et al.
JOURNAL OF IMMUNOLOGY (2013)
Deubiquitination of NLRP3 by BRCC3 Critically Regulates Inflammasome Activity
Benedicte F. Py et al.
MOLECULAR CELL (2013)
Nitric oxide controls the immunopathology of tuberculosis by inhibiting NLRP3 inflammasome-dependent processing of IL-1 beta
Bibhuti B. Mishra et al.
NATURE IMMUNOLOGY (2013)
Microtubule-driven spatial arrangement of mitochondria promotes activation of the NLRP3 inflammasome
Takuma Misawa et al.
NATURE IMMUNOLOGY (2013)
Triggering of Inflammasome by Aggregated α-Synuclein, an Inflammatory Response in Synucleinopathies
Gaia Codolo et al.
PLOS ONE (2013)
Mitochondrial protein mitofusin 2 is required for NLRP3 inflammasome activation after RNA virus infection
Takeshi Ichinohe et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Cytoplasmic LPS Activates Caspase-11: Implications in TLR4-Independent Endotoxic Shock
Jon A. Hagar et al.
SCIENCE (2013)
Noncanonical Inflammasome Activation by Intracellular LPS Independent of TLR4
Nobuhiko Kayagaki et al.
SCIENCE (2013)
TRPM2 links oxidative stress to NLRP3 inflammasome activation
Zhenyu Zhong et al.
NATURE COMMUNICATIONS (2013)
Cellular localization of NLRP3 inflammasome
Yan Wang et al.
PROTEIN & CELL (2013)
Cell Volume Regulation Modulates NLRP3 Inflammasome Activation
Vincent Compan et al.
IMMUNITY (2012)
The NLRP12 Inflammasome Recognizes Yersinia pestis
Gregory I. Vladimer et al.
IMMUNITY (2012)
An NLRP7-Containing Inflammasome Mediates Recognition of Microbial Lipopeptides in Human Macrophages
Sonal Khare et al.
IMMUNITY (2012)
Oxidized Mitochondrial DNA Activates the NLRP3 Inflammasome during Apoptosis
Kenichi Shimada et al.
IMMUNITY (2012)
Acute lipopolysaccharide priming boosts inflammasome activation independently of inflammasome sensor induction
Kate Schroder et al.
IMMUNOBIOLOGY (2012)
Multiple Binding Sites on the Pyrin Domain of ASC Protein Allow Self-association and Interaction with NLRP3 Protein
Parimala R. Vajjhala et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Non-transcriptional Priming and Deubiquitination Regulate NLRP3 Inflammasome Activation
Christine Juliana et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Cutting Edge: Nitric Oxide Inhibits the NLRP3 Inflammasome
Eduardo Hernandez-Cuellar et al.
JOURNAL OF IMMUNOLOGY (2012)
Caspase-11 increases susceptibility to Salmonella infection in the absence of caspase-1
Petr Broz et al.
NATURE (2012)
Novel role of PKR in inflammasome activation and HMGB1 release
Ben Lu et al.
NATURE (2012)
The calcium-sensing receptor regulates the NLRP3 inflammasome through Ca2+ and cAMP
Geun-Shik Lee et al.
NATURE (2012)
Critical role for calcium mobilization in activation of the NLRP3 inflammasome
Tomohiko Murakami et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
GBP5 Promotes NLRP3 Inflammasome Assembly and Immunity in Mammals
Avinash R. Shenoy et al.
SCIENCE (2012)
NLRP6 Inflammasome Regulates Colonic Microbial Ecology and Risk for Colitis
Eran Elinav et al.
CELL (2011)
IFI16 Acts as a Nuclear Pathogen Sensor to Induce the Inflammasome in Response to Kaposi Sarcoma-Associated Herpesvirus Infection
Nagaraj Kerur et al.
CELL HOST & MICROBE (2011)
The NLRP3 inflammasome in health and disease: the good, the bad and the ugly
P. Menu et al.
CLINICAL AND EXPERIMENTAL IMMUNOLOGY (2011)
Sodium Overload and Water Influx Activate the NALP3 Inflammasome
Christine Schorn et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Cutting Edge: Reactive Oxygen Species Inhibitors Block Priming, but Not Activation, of the NLRP3 Inflammasome
Franz Bauernfeind et al.
JOURNAL OF IMMUNOLOGY (2011)
Adenovirus Membrane Penetration Activates the NLRP3 Inflammasome
A. U. Barlan et al.
JOURNAL OF VIROLOGY (2011)
A role for mitochondria in NLRP3 inflammasome activation
Rongbin Zhou et al.
NATURE (2011)
Non-canonical inflammasome activation targets caspase-11
Nobuhiko Kayagaki et al.
NATURE (2011)
Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome
Kiichi Nakahira et al.
NATURE IMMUNOLOGY (2011)
The inflammasomes: molecular effectors of host resistance against bacterial, viral, parasitic, and fungal infections
Alexander Skeldon et al.
FRONTIERS IN MICROBIOLOGY (2011)
Human NLRP3 inflammasome activation is Nox1-4 independent
Robin van Bruggen et al.
BLOOD (2010)
Pattern Recognition Receptors and Inflammation
Osamu Takeuchi et al.
CELL (2010)
Nlrp3: An immune sensor of cellular stress and infection
Mohamed Lamkanfi et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2010)
NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals
Peter Duewell et al.
NATURE (2010)
Thioredoxin-interacting protein links oxidative stress to inflammasome activation
Rongbin Zhou et al.
NATURE IMMUNOLOGY (2010)
Caspase-1-induced pyroptosis is an innate immune effector mechanism against intracellular bacteria
Edward A. Miao et al.
NATURE IMMUNOLOGY (2010)
Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1 beta in type 2 diabetes
Seth L. Masters et al.
NATURE IMMUNOLOGY (2010)
Nek7 kinase targeting leads to early mortality, cytokinesis disturbance and polyploidy
H. Salem et al.
ONCOGENE (2010)
Immunological and Inflammatory Functions of the Interleukin-1 Family
Charles A. Dinarello
ANNUAL REVIEW OF IMMUNOLOGY (2009)
Differential requirement for the activation of the inflammasome for processing and release of IL-1β in monocytes and macrophages
Mihai G. Netea et al.
BLOOD (2009)
The NLRP3 Inflammasome Mediates In Vivo Innate Immunity to Influenza A Virus through Recognition of Viral RNA
Irving C. Allen et al.
IMMUNITY (2009)
A Mutation in the Nlrp3 Gene Causing Inflammasome Hyperactivation Potentiates Th17 Cell-Dominant Immune Responses
Guangxun Meng et al.
IMMUNITY (2009)
The Intracellular Sensor NLRP3 Mediates Key Innate and Healing Responses to Influenza A Virus via the Regulation of Caspase-1
Paul G. Thomas et al.
IMMUNITY (2009)
Function of Nod-like receptors in microbial recognition and host defense
Luigi Franchi et al.
IMMUNOLOGICAL REVIEWS (2009)
Cutting Edge: TNF-α Mediates Sensitization to ATP and Silica via the NLRP3 Inflammasome in the Absence of Microbial Stimulation
Luigi Franchi et al.
JOURNAL OF IMMUNOLOGY (2009)
Cutting Edge: NF-κB Activating Pattern Recognition and Cytokine Receptors License NLRP3 Inflammasome Activation by Regulating NLRP3 Expression
Franz G. Bauernfeind et al.
JOURNAL OF IMMUNOLOGY (2009)
Cholesterol-dependent cytolysins induce rapid release of mature IL-1β from murine macrophages in a NLRP3 inflammasome and cathepsin B-dependent manner
Jessica Chu et al.
JOURNAL OF LEUKOCYTE BIOLOGY (2009)
Syk kinase signalling couples to the Nlrp3 inflammasome for anti-fungal host defence
Olaf Gross et al.
NATURE (2009)
The inflammasome: a caspase-1-activation platform that regulates immune responses and disease pathogenesis
Luigi Franchi et al.
NATURE IMMUNOLOGY (2009)
Malarial Hemozoin Is a Nalp3 Inflammasome Activating Danger Signal
Catherine Dostert et al.
PLOS ONE (2009)
Alum adjuvant stimulates inflammatory dendritic cells through activation of the NALP3 inflammasome
Mirjam Kool et al.
JOURNAL OF IMMUNOLOGY (2008)
Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization
Veit Hornung et al.
NATURE IMMUNOLOGY (2008)
The NALP3 inflammasome is involved in the innate immune response to amyloid-β
Annett Halle et al.
NATURE IMMUNOLOGY (2008)
The Nalp3 inflammasome is essential for the development of silicosis
Suzanne L. Cassel et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
ATP is released by monocytes stimulated with pathogen-sensing receptor ligands and induces IL-1β and IL-18 secretion in an autocrine way
Alessandra Piccini et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica
Catherine Dostert et al.
SCIENCE (2008)
Activation of the NALP3 inflammasome is triggered by low intracellular potassium concentration
V. Petrilli et al.
CELL DEATH AND DIFFERENTIATION (2007)
The pyroptosome: a supramolecular assembly of ASC dimers mediating inflammatory cell death via caspase-1 activation
T. Fernandes-Alnemri et al.
CELL DEATH AND DIFFERENTIATION (2007)
The inflammasome mediates UVB-Induced activation and secretion of interleukin-1β by keratinocytes
Laurence Feldmeyer et al.
CURRENT BIOLOGY (2007)
Cryopyrin/NALP3 binds ATP/dATP, is an ATPase, and requires ATP binding to mediate inflammatory signaling
Joseph A. Duncan et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
A crucial function of SGT1 and HSP90 in inflammasome activity links mammalian and plant innate immune responses
Annick Mayor et al.
NATURE IMMUNOLOGY (2007)
Essential role for caspase-8 in toll-like receptors and NFκB signaling
Benedicte Lemmers et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
ATP activates a reactive oxygen species-dependent oxidative stress response and secretion of proinflammatory cytokines in macrophages
Cristiane M. Cruz et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Critical role for Cryopyrin/Nalp3 in activation of caspase-1 in response to viral infection and double-stranded RNA
Thirumala-Devi Kanneganti et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Pannexin-1 mediates large pore formation and interleukin-1β release by the ATP-gated P2X7 receptor
Pablo Pelegrin et al.
EMBO JOURNAL (2006)
Caspase-1-dependent pore formation during pyroptosis leads to osmotic lysis of infected host macrophages
Susan L. Fink et al.
CELLULAR MICROBIOLOGY (2006)
Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3
TD Kanneganti et al.
NATURE (2006)
Cryopyrin activates the inflammasome in response to toxins and ATP
S Mariathasan et al.
NATURE (2006)
Gout-associated uric acid crystals activate the NALP3 inflammasome
F Martinon et al.
NATURE (2006)
Ca2+ stores and Ca2+ entry differentially contribute to the release of IL-1β and IL-1α from murine macrophages
D Brough et al.
JOURNAL OF IMMUNOLOGY (2003)
The inflammasome:: A molecular platform triggering activation of inflammatory caspases and processing of proIL-β
F Martinon et al.
MOLECULAR CELL (2002)
PYPAF1, a PYRIN-containing Apaf1-like protein that assembles with ASC and regulates activation of NF-κB
GA Manji et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Potassium regulates IL-1β processing via calcium-independent phospholipase A2
I Walev et al.
JOURNAL OF IMMUNOLOGY (2000)
分享论文
