期刊
BIOMEDICAL CHROMATOGRAPHY
卷 30, 期 1, 页码 13-28出版社
WILEY
DOI: 10.1002/bmc.3529
关键词
allantoin; antioxidants; ascorbic acid; coenzyme Q(10); glutathione; oxidative stress
类别
资金
- Czech Ministry of Education [SGSFChT_2014005]
Oxidative stress is an imbalance between reactive oxygen species exposure and the ability of organisms to detoxify the reactive intermediates and to repair the oxidative damage of biologically important molecules. Many clinical studies of oxidative stress unfortunately provide conflicting and contradictory results. The ability of antioxidant systems to adequately respond to oxidative stress can be used in laboratory diagnostics. In the present review, methods using the ratio of reduced and oxidized forms of uric acid, ascorbic acid, glutathione and coenzyme Q(10) as suitable indicators of oxidative stress are discussed. From the mentioned publications it is evident that suitable sample preparation prior to analysis is crucial. Copyright (c) 2015 John Wiley & Sons, Ltd.
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