期刊
FOOD CHEMISTRY
卷 286, 期 -, 页码 686-695出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.foodchem.2019.02.049
关键词
Vitis vinifera L.; Winery by-products; Waste; LC-MS/MS; Antioxidant activity; Neuroprotective activity; Anti-acetylcholiesterase activity; Cytotoxic activity
资金
- Ministry of Education, Science and Technological Development of the Republic of Serbia [172058]
- Provincial Secretariat for Science and Technological Development, Autonomous Province of Vojvodina [114-451-1752/2014-02]
Chemical composition and bioactivity of eight edible Vitis vinifera L. leaf varieties originating from Fruska Gora, Serbia, including two autochthonous varieties, were evaluated. The LC-MS/MS analysis confirmed the presence of 28 natural products in leaf samples, among which most abundant were glycosylated flavonoids, ellagic and chlorogenic acids. The highest amounts of most of the tested compounds were detected in leaves of autochthonous variety Sila. Bioactivity was assessed by a set of in vitro antioxidant, neuroprotective and cytotoxic assays. Leaves of all examined varieties exhibited average bioactivity, with leaves of autochthonous variety Zupljanka standing out as the most promising sample. To conclude, investigated grapevine leaves proved to be a rich source of nutraceuticals, primarily antioxidants, and their further employment as medicinal food in human diet and beneficial raw material for food, pharmaceutical and cosmetic industries should be supported.
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