期刊
DIGESTIVE AND LIVER DISEASE
卷 51, 期 9, 页码 1265-1269出版社
ELSEVIER SCIENCE INC
DOI: 10.1016/j.dld.2019.05.024
关键词
Crohn's disease; Nutritional status; Telemedicine; Ulcerative colitis
资金
- academic incentive fund of the Maastricht University Medical Centre+ [31962340B]
- Ferring
Background: Inflammatory bowel disease (IBD) patients are at risk of an impaired nutritional status. The impact thereof on the IBD relapse risk is clinically relevant, though sparsely investigated. Aim: The aim was to explore the association between an impaired nutritional status risk and the occurrence of disease flares in IBD outpatients participating in a longitudinal telemedicine study. Methods: IBD outpatients were recruited from the myIBDcoach study cohort, with one year clinical follow-up. Through myIBDcoach, a telemedicine tool, patients reported on disease activity and risk of impaired nutritional status (i.e. Short Nutritional Assessment Questionnaire > 1 and/or BMI < 18.5 kg/m(2)) every one to three months. Data was analysed by generalized estimating equation modelling. Results: In total, 417 patients were included. During follow-up, 49 patients (11.8%) flared after initial clinical remission and 53 patients (12.7%) showed an increased risk of impaired nutritional status. The risk of impaired nutritional status was associated with flare occurrence (OR 2.61 (95% CI 1.02-6.69)). Conclusions: The risk of an impaired nutritional status was associated with subsequent flares in IBD outpatients. This emphasizes the importance of monitoring disease activity in IBD patients at risk of impaired nutritional status. (C) 2019 Editrice Gastroenterologica Italiana S.r.l. Published by Elsevier Ltd. All rights reserved.
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