期刊
DERMATOLOGIC CLINICS
卷 37, 期 3, 页码 241-+出版社
W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1016/j.det.2019.03.009
关键词
Cutaneous squamous cell carcinoma; High-risk skin cancer; AJCC staging; Squamous cell carcinoma staging; Skin cancer radiologic imaging; Sentinel lymph node biopsy; PD-1 inhibitor; EGFR inhibitor
类别
Cutaneous squamous cell carcinoma (cSCC) is one of the most common cancers in the United States. Outcomes are generally favorable, but a subset of cSCC is bio-logically distinct and requires a different approach because of its higher risk of local recurrence, metastasis, and death. This article focuses on the recent literature regarding identification of this high-risk subset, efforts to validate and improve the prognostic ability of staging systems, and updates in management.
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