Precise Manipulation of Temperature-Driven Chirality Switching of Molecular Universal Joints through Solvent Mixing

Temperature-driven chirality switching of three pillar[5]arene-based molecular universal joints (MUJs) was precisely manipulated by mixing two miscible organic solvents, in each of which chirality inversion is not accomplishable. Solvent mixing drastically varied the inversion temperature of MUJs, and the temperature-driven chirality switching direction could be critically controlled by mixing the ratios of two solvents. More information can be found in the Full Paper by W. Wu, C. Yang, et al. (DOI: 10.1002/chem.201902676).