相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Brain metabolic sensing and metabolic signaling at the level of an astrocyte
Nephtali Marina et al.
GLIA (2018)
Exploring the genetics and non-cell autonomous mechanisms underlying ALS/FTLD
Hongbo Chen et al.
CELL DEATH AND DIFFERENTIATION (2018)
NF-κB activation in astrocytes drives a stage-specific beneficial neuroimmunological response in ALS
Najwa Ouali Alami et al.
EMBO JOURNAL (2018)
Inducible nitric oxide synthase inhibition by 1400W limits pain hypersensitivity in a neuropathic pain rat model
C. A. Staunton et al.
EXPERIMENTAL PHYSIOLOGY (2018)
The Aging Astrocyte Transcriptome from Multiple Regions of the Mouse Brain
Matthew M. Boisvert et al.
CELL REPORTS (2018)
Mass spectrometry analysis of plasma from amyotrophic lateral sclerosis and control subjects
Zhouwei Xu et al.
AMYOTROPHIC LATERAL SCLEROSIS AND FRONTOTEMPORAL DEGENERATION (2018)
Reactive Astrocytes: Production, Function, and Therapeutic Potential
Shane A. Liddelow et al.
IMMUNITY (2017)
Neurotoxic reactive astrocytes are induced by activated microglia
Shane A. Liddelow et al.
NATURE (2017)
Neural Circuit-Specialized Astrocytes: Transcriptomic, Proteomic, Morphological, and Functional Evidence
Hua Chai et al.
NEURON (2017)
Cellular Chaperones As Therapeutic Targets in ALS to Restore Protein Homeostasis and Improve Cellular Function.
Bernadett Kalmar et al.
FRONTIERS IN MOLECULAR NEUROSCIENCE (2017)
Astrocytes Surviving Severe Stress Can Still Protect Neighboring Neurons from Proteotoxic Injury
Amanda M. Gleixner et al.
MOLECULAR NEUROBIOLOGY (2016)
Disturbance of proteasomal and autophagic protein degradation pathways by amyotrophic lateral sclerosis-linked mutations in ubiquilin 2
Mayuko Osaka et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2016)
Non-neuronal Cells in ALS: Role of Glial, Immune cells and Blood-CNS Barriers
Fabiola Puentes et al.
BRAIN PATHOLOGY (2016)
Impact of Heat Shock Protein A 12B Overexpression on Spinal Astrocyte Survival Against Oxygen-Glucose-Serum Deprivation/Restoration in Primary Cultured Astrocytes
Xun Xia et al.
JOURNAL OF MOLECULAR NEUROSCIENCE (2016)
A Surveillance Function of the HSPB8-BAG3-HSP70 Chaperone Complex Ensures Stress Granule Integrity and Dynamism
Massimo Ganassi et al.
MOLECULAR CELL (2016)
Microglial brain region-dependent diversity and selective regional sensitivities to aging
Kathleen Grabert et al.
NATURE NEUROSCIENCE (2016)
Functional diversity of astrocytes in neural circuit regulation
Lucile Ben Haim et al.
NATURE REVIEWS NEUROSCIENCE (2016)
Transcriptomic analyses of primary astrocytes under TNFα treatment
Cindy Birck et al.
GENOMICS DATA (2016)
NF-κB deficit in spinal motoneurons in patients with sporadic amyotrophic lateral sclerosis - a pilot study
Dorota Sulejczak et al.
FOLIA NEUROPATHOLOGICA (2015)
Antagonistic pleiotropic effects of nitric oxide in the pathophysiology of Parkinson's disease
D. Tripathy et al.
FREE RADICAL RESEARCH (2015)
Pharmacologic Heat Shock Protein 70 Induction Confers Cytoprotection against Inflammation in Gliovascular Cells
Rachid Kacimi et al.
GLIA (2015)
Diversity of astrocyte functions and phenotypes in neural circuits
Baljit S. Khakh et al.
NATURE NEUROSCIENCE (2015)
REGULATION OF INFLAMMATORY TRANSCRIPTION FACTORS BY HEAT SHOCK PROTEIN 70 IN PRIMARY CULTURED ASTROCYTES EXPOSED TO OXYGEN-GLUCOSE DEPRIVATION
J. Y. Kim et al.
NEUROSCIENCE (2015)
Protective and Toxic Neuroinflammation in Amyotrophic Lateral Sclerosis
Kristopher G. Hooten et al.
NEUROTHERAPEUTICS (2015)
Coupling of Ribostasis and Proteostasis: Hsp70 Proteins in mRNA Metabolism
Robert W. Walters et al.
TRENDS IN BIOCHEMICAL SCIENCES (2015)
Astrocyte heterogeneity in the brain: from development to disease
Clarissa Schitine et al.
FRONTIERS IN CELLULAR NEUROSCIENCE (2015)
Implications of glial nitric oxide in neurodegenerative diseases
Jose Enrique Yuste et al.
FRONTIERS IN CELLULAR NEUROSCIENCE (2015)
The Regulatory Machinery of Neurodegeneration in In Vitro Models of Amyotrophic Lateral Sclerosis
Burcin Ikiz et al.
CELL REPORTS (2015)
Astrocyte-encoded positional cues maintain sensorimotor circuit integrity
Anna V. Molofsky et al.
NATURE (2014)
Necroptosis Drives Motor Neuron Death in Models of Both Sporadic and Familial ALS
Diane B. Re et al.
NEURON (2014)
Microglia Induce Motor Neuron Death via the Classical NF-κB Pathway in Amyotrophic Lateral Sclerosis
Ashley E. Frakes et al.
NEURON (2014)
The role of heat shock proteins in Amyotrophic Lateral Sclerosis: The therapeutic potential of Arimoclomol
Bernadett Kalmar et al.
PHARMACOLOGY & THERAPEUTICS (2014)
Nuclear factor k B expression in patients with sporadic amyotrophic lateral sclerosis and hereditary amyotrophic lateral sclerosis with optineurin mutations
Wataru Sako et al.
CLINICAL NEUROPATHOLOGY (2012)
Nitric Oxide-Mediated Oxidative Damage and the Progressive Demise of Motor Neurons in ALS
Derek A. Drechsel et al.
NEUROTOXICITY RESEARCH (2012)
Dysregulation of astrocyte-motoneuron cross-talk in mutant superoxide dismutase 1-related amyotrophic lateral sclerosis
Laura Ferraiuolo et al.
BRAIN (2011)
Proteins That Bind to Misfolded Mutant Superoxide Dismutase-1 in Spinal Cords from Transgenic Amyotrophic Lateral Sclerosis (ALS) Model Mice
Per Zetterstrom et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Neuroinflammation in amyotrophic lateral sclerosis: role of glial activation in motor neuron disease
Thomas Philips et al.
LANCET NEUROLOGY (2011)
Astrocytes from familial and sporadic ALS patients are toxic to motor neurons
Amanda M. Haidet-Phillips et al.
NATURE BIOTECHNOLOGY (2011)
Astroglial Inhibition of NF-κB Does Not Ameliorate Disease Onset and Progression in a Mouse Model for Amyotrophic Lateral Sclerosis (ALS)
Claudia Crosio et al.
PLOS ONE (2011)
Inducible nitric oxide synthase is present in motor neuron mitochondria and Schwann cells and contributes to disease mechanisms in ALS mice
Kevin Chen et al.
BRAIN STRUCTURE & FUNCTION (2010)
Astrocyte heterogeneity: an underappreciated topic in neurobiology
Ye Zhang et al.
CURRENT OPINION IN NEUROBIOLOGY (2010)
Chaperone-mediated autophagy in health and disease
Maria Kon et al.
FEBS LETTERS (2010)
Astrocyte Targeted Overexpression of Hsp72 or SOD2 Reduces Neuronal Vulnerability to Forebrain Ischemia
Lijun Xu et al.
GLIA (2010)
Identification of positionally distinct astrocyte subtypes whose identities are specified by a homeodomain code
Christian Hochstim et al.
CELL (2008)
Shared principles in NF-κB signaling
Matthew S. Hayden et al.
CELL (2008)
Region-specific expression of immunoregulatory proteins on microglia in the healthy CNS
Alexander H. De Haas et al.
GLIA (2008)
Expression of mutant SOD1G93A in astrocytes induces functional deficits in motoneuron mitochondria
Lynsey G. Bilsland et al.
JOURNAL OF NEUROCHEMISTRY (2008)
Astrocytes as determinants of disease progression in inherited amyotrophic lateral sclerosis
Koji Yamanaka et al.
NATURE NEUROSCIENCE (2008)
Anti-inflammatory effects of the 70 kDa heat shock protein in experimental stroke
Zhen Zheng et al.
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2008)
Exogenous delivery of heat shock protein 70 increases lifespan in a mouse model of amyotrophic lateral sclerosis
David J. Gifondorwa et al.
JOURNAL OF NEUROSCIENCE (2007)
Variations in promoter activity reveal a differential expression and physiology of glutamate transporters by glia in the developing and mature CNS
Melissa R. Regan et al.
JOURNAL OF NEUROSCIENCE (2007)
Astrocytes expressing ALS-linked mutated SOD1 release factors selectively toxic to motor neurons
Makiko Nagai et al.
NATURE NEUROSCIENCE (2007)
Motor neuron degeneration in amyotrophic lateral sclerosis mutant superoxide dismutase-1 transgenic mice: Mechanisms of mitochondriopathy and cell death
Lee J. Martin et al.
JOURNAL OF COMPARATIVE NEUROLOGY (2007)
Biphasic role of nuclear factor-κ B on cell survival and COX-2 expression in SOD1 Tg astrocytes after oxygen glucose deprivation
Yong-Sun Lee et al.
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2006)
Ascending neuropathology in the CNS of a mutant SOD1 mouse model of amyotrophic lateral sclerosis
Anna Leichsenring et al.
BRAIN RESEARCH (2006)
Onset and progression in inherited ALS determined by motor neurons and microglia
Severine Boillee et al.
SCIENCE (2006)
Hsp70 inhibits lipopolysaccharide-induced NF-κB activation by interacting with TRAF6 and inhibiting its ubiquitination
Huaqun Chen et al.
FEBS LETTERS (2006)
Alteration of familial ALS-linked mutant SOD1 solubility with disease progression: Its modulation by the proteasome and Hsp70
S Koyama et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2006)
Adenosine A2A receptor stimulation potentiates nitric oxide release by activated microglia
J Saura et al.
JOURNAL OF NEUROCHEMISTRY (2005)
Extracellular heat shock protein 70: A critical component for motoneuron survival
MB Robinson et al.
JOURNAL OF NEUROSCIENCE (2005)
17-AAG, an Hsp90 inhibitor, ameliorates polyglutamine-mediated motor neuron degeneration
M Waza et al.
NATURE MEDICINE (2005)
1400W, a potent selective inducible NOS inhibitor, improves hi stop atholo gical outcome following traumatic brain injury in rats
M Jafarian-Tehrani et al.
NITRIC OXIDE-BIOLOGY AND CHEMISTRY (2005)
An ELISA for glial fibrillary acidic protein
A Petzold et al.
JOURNAL OF IMMUNOLOGICAL METHODS (2004)
Treatment with arimoclomol, a coinducer of heat shock proteins, delays disease progression in ALS mice
D Kieran et al.
NATURE MEDICINE (2004)
Heat shock protein 70 participates in the neuroprotective response to intracellularly expressed β-amyloid in neurons
J Magrané et al.
JOURNAL OF NEUROSCIENCE (2004)
Hsp70 promotes TNF-mediated apoptosis by binding IKKγ and impairing NF-κB survival signaling
RQ Ran et al.
GENES & DEVELOPMENT (2004)
Focal dysfunction of the proteasome: a pathogenic factor in a mouse model of amyotrophic lateral sclerosis
E Kabashi et al.
JOURNAL OF NEUROCHEMISTRY (2004)
Oxidative modulation of nuclear factor-κB in human cells expressing mutant fALS-typical superoxide dismutases
A Casciati et al.
JOURNAL OF NEUROCHEMISTRY (2002)
Amyotrophic lateral sclerosis: A proposed mechanism
A Okado-Matsumoto et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Suppressive effects of ansamycins on inducible nitric oxide synthase expression and the development of experimental autoimmune encephalomyelitis
P Murphy et al.
JOURNAL OF NEUROSCIENCE RESEARCH (2002)
Histological evidence of protein aggregation in mutant SOD1 transgenic mice and in amyotrophic lateral sclerosis neural tissues
M Watanabe et al.
NEUROBIOLOGY OF DISEASE (2001)
In vitro studies show that Hsp70 can be released by glia and that exogenous Hsp70 can enhance neuronal stress tolerance
I Guzhova et al.
BRAIN RESEARCH (2001)
β-amyloid stimulation of inducible nitric-oxide synthase in astrocytes is interleukin-1β- and tumor necrosis factor-α (TNFα)-dependent, and involves a TNFα receptor-associated factor- and NFκB-inducing kinase-dependent signaling mechanism
KT Akama et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
The ubiquitin-related BAG-1 provides a link between the molecular chaperones Hsc70/Hsp70 and the proteasome
J Lüders et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)