期刊
CARBOHYDRATE POLYMERS
卷 215, 期 -, 页码 307-315出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.carbpol.2019.03.099
关键词
Mallotus furetianus (Bail) Muell Arg; Polysaccharide; Structural characterization; Antioxidant ability; alpha-Glucosidase
资金
- National Key R&D Program of China [2016YFD0400303]
- Natural Science Foundation of Guangdong Province [2017A030311021]
- Guangdong Province YangFan Innovative and Enterpreneurial Research Team Project [2014YT02S029]
A purified polysaccharide, designated as MFP-2A, was isolated from Mallotus furetianus (Bail) Muell Arg. The primary structure characteristics were determined by HPGPC, HPLC, FT-IR, methylation analysis, NMR, SEM and AFM. The results showed that MFP-2A was a homogeneous heteropolysaccharide with an average molecular weight of 25.96 KDa. The monosaccharide composition was consisted of mannose, galactose, arabinose, galacturonic acid and glucose with a molar ratio of 3.05:2.84:1.84:0.86:1.41. In addition, methylation and NMR analysis revealed that the main glycosidic bonds of MFP-2A were comprised of 1,4,6-linked-beta-D-Galp, 1,3,6-linked-beta-D-Manp, 1,5-linked-alpha-L-Araf, 1-linked-alpha-L-Araf, 1,4-linked-alpha-D-GalAp and 1,4-linked-alpha-D-Glcp residues. Moreover, MFP-2A also exhibited significant free radical scavenging ability and alpha-glucosidase inhibitory activities in vitro. Overall, these results demonstrated that MFP-2A from Mallotus furetianus (Bail) Muell Arg could serve as a potential anti-diabetic and functional food.
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