期刊
CARBOHYDRATE POLYMERS
卷 213, 期 -, 页码 128-137出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.carbpol.2019.02.064
关键词
Cellulose nanocrystals; Redispersible Pickering emulsions; Carboxymethyl cellulose sodium; Hydroxypropyl methylcellulose; Homogenization
资金
- Scientific Research Foundation for the National Natural Science Foundation of China [81760715]
- Young Jinggang Scholar Award Program
- Fund of Distinguished Young Scientists of Jiangxi Province [20162BCB23033]
The objective of this study is to use cellulose nanocrystals (CNC) combining with carboxymethyl cellulose sodium (CMC-Na) and hydroxypropyl methylcellulose (HPMC) as stabilizer to prepare novel redispersible camellia oil Pickering emulsions powder (CO-PEP). Cellulose nanocrystals modified with carboxymethyl cellulose sodium (CNCC) was prepared by homogenization technology. CNCC seemed to be rod-like particles with mean particle size of 124.2 +/- 2.5 nm. And the cellulose structure, crystal state and thermal property of CNCC remained unchanged during the homogenization. The combination of CNC and CMC-Na in CNCC might be dependent of physical interaction. The mean particle size of optimum CO-PE/0.25% CNCC was 0.569 +/- 0.023 mu m. The CNCC based particle stabilizer might form the distinctive barrier layer around oil droplet. The redispersibility results demonstrated that 50% HPMC based CO-PEP formed large composite particle with high drug loading ability and exhibited superior redispersibility. Novel redispersible powdered Pickering emulsions could be prepared by cellulose nanocrystals combining with water-soluble cellulosic derivatives.
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