相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。High Glucose Triggers Nucleotide Imbalance through O-GlcNAcylation of Key Enzymes and Induces KRAS Mutation in Pancreatic Cells
Chun-Mei Hu et al.
CELL METABOLISM (2019)
O-GlcNAc transferase activates stem-like cell potential in hepatocarcinoma through O-GlcNAcylation of eukaryotic initiation factor 4E
Benjin Cao et al.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2019)
O-GlcNAcylation Enhances Double-Strand Break Repair, Promotes Cancer Cell Proliferation, and Prevents Therapy-Induced Senescence in Irradiated Tumors
Elena Efimova et al.
MOLECULAR CANCER RESEARCH (2019)
New insights into the mechanisms of epithelial-mesenchymal transition and implications for cancer
Anushka Dongre et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2019)
IL-8-induced O-GlcNAc modification via GLUT3 and GFAT regulates cancer stem cell-like properties in colon and lung cancer cells
Masahiro Shimizu et al.
ONCOGENE (2019)
Nutrient sensor O-GlcNAc transferase controls cancer lipid metabolism via SREBP-1 regulation
V. L. Sodi et al.
ONCOGENE (2018)
Metabolic Inhibitors of O-GlcNAc Transferase That Act In Vivo Implicate Decreased O-GlcNAc Levels in Leptin-Mediated Nutrient Sensing
Tai-Wei Liu et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2018)
2-Deoxy-D-glucose increases GFAT1 phosphorylation resulting in endoplasmic reticulum-related apoptosis via disruption of protein N-glycosylation in pancreatic cancer cells
Kousuke Ishino et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2018)
Thio-Linked UDP-Peptide Conjugates as O-GlcNAc Transferase Inhibitors
Karim Rafie et al.
BIOCONJUGATE CHEMISTRY (2018)
O-GlcNAcylation of the Tumor Suppressor FOXO3 Triggers Aberrant Cancer Cell Growth
Heon Shin et al.
CANCER RESEARCH (2018)
Cross regulation between mTOR signaling and O-GlcNAcylation
Ninon Very et al.
JOURNAL OF BIOENERGETICS AND BIOMEMBRANES (2018)
Inhibition of the Hexosamine Biosynthetic Pathway by targeting PGM3 causes breast cancer growth arrest and apoptosis
Francesca Ricciardiello et al.
CELL DEATH & DISEASE (2018)
The Nutrient-Sensing Hexosamine Biosynthetic Pathway as the Hub of Cancer Metabolic Rewiring
Ferdinando Chiaradonna et al.
CELLS (2018)
DNA Damage, Repair, and Cancer Metabolism
Marc-Olivier Turgeon et al.
FRONTIERS IN ONCOLOGY (2018)
Transcriptional regulation of O-GlcNAc homeostasis is disrupted in pancreatic cancer
Kevin Qian et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2018)
mTORC2 modulates the amplitude and duration of GFAT1 Ser-243 phosphorylation to maintain flux through the hexosamine pathway during starvation
Joseph G. Moloughney et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2018)
Hexosamine Biosynthetic Pathway Inhibition Leads to AML Cell Differentiation and Cell Death
Abhishek Asthana et al.
MOLECULAR CANCER THERAPEUTICS (2018)
Reciprocal Regulation of Metabolic Reprogramming and Epigenetic Modifications in Cancer
Xian Yu et al.
FRONTIERS IN GENETICS (2018)
Real Talk: The Inter-play Between the mTOR, AMPK, and Hexosamine Biosynthetic Pathways in Cell Signaling
Gentry K. Cork et al.
FRONTIERS IN ENDOCRINOLOGY (2018)
Cellular glycosylation senses metabolic changes and modulates cell plasticity during epithelial to mesenchymal transition
Patricia Carvalho-cruz et al.
DEVELOPMENTAL DYNAMICS (2018)
GFAT1 phosphorylation by AMPK promotes VEGF-induced angiogenesis
Darya Zibrova et al.
BIOCHEMICAL JOURNAL (2017)
Breast cancer stem cell: the roles and therapeutic implications
Fang Yang et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2017)
O-GlcNAcylation regulates breast cancer metastasis via SIRT1 modulation of FOXM1 pathway
C. M. Ferrer et al.
ONCOGENE (2017)
O-GlcNAc transferase regulates transcriptional activity of human Oct4
Sandii Constable et al.
GLYCOBIOLOGY (2017)
O-Linked N-Acetylglucosamine (O-GlcNAc) Expression Levels Epigenetically Regulate Colon Cancer Tumorigenesis by Affecting the Cancer Stem Cell Compartment via Modulating Expression of Transcriptional Factor MYBL1
Huabei Guo et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2017)
Regulation of the Hippo-YAP Pathway by Glucose Sensor O-GlcNAcylation
Changmin Peng et al.
MOLECULAR CELL (2017)
O-GlcNAcylation of fumarase maintains tumour growth under glucose deficiency
Ting Wang et al.
NATURE CELL BIOLOGY (2017)
O-GlcNAcylation modulates Bmi-1 protein stability and potential oncogenic function in prostate cancer
Y. Li et al.
ONCOGENE (2017)
Nesting of colon and ovarian cancer cells in the endothelial niche is associated with alterations in glycan and lipid metabolism
Anna Halama et al.
SCIENTIFIC REPORTS (2017)
A Conserved Splicing Silencer Dynamically Regulates O-GlcNAc Transferase Intron Retention and O-GlcNAc Homeostasis
Sung-Kyun Park et al.
CELL REPORTS (2017)
Hyperglycemia exacerbates colon cancer malignancy through hexosamine biosynthetic pathway
A. Vasconcelos-dos-Santos et al.
ONCOGENESIS (2017)
Roles of Integrin α6β4 Glycosylation in Cancer
Yoshinobu Kariya et al.
CANCERS (2017)
Hyper-O-nGlcNAcylation induces cisplatin resistance via regulation of p53 and c-Myc in human lung carcinoma
Sudjit Luanpitpong et al.
SCIENTIFIC REPORTS (2017)
FOXO transcription factors in cancer development and therapy
Alexandra Coomans de Brachene et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2016)
Preventing E-cadherin aberrant N-glycosylation at Asn-554 improves its critical function in gastric cancer
S. Carvalho et al.
ONCOGENE (2016)
O-GlcNAc transferase inhibitors: current tools and future challenges
Riccardo Trapannone et al.
BIOCHEMICAL SOCIETY TRANSACTIONS (2016)
Metabolic Heterogeneity in Human Lung Tumors
Christopher T. Hensley et al.
CELL (2016)
Epithelial Mesenchymal Transition Induces Aberrant Glycosylation through Hexosamine Biosynthetic Pathway Activation
Miguel C. Lucena et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2016)
Hyaluronan Production Regulates Metabolic and Cancer Stem-like Properties of Breast Cancer Cells via Hexosamine Biosynthetic Pathway-coupled HIF-1 Signaling
Theerawut Chanmee et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2016)
Changes in O-Linked N-Acetylglucosamine (O-GlcNAc) Homeostasis Activate the p53 Pathway in Ovarian Cancer Cells
Rafaela Muniz de Queiroz et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2016)
Global Analysis of O-GlcNAc Glycoproteins in Activated Human T Cells
Peder J. Lund et al.
JOURNAL OF IMMUNOLOGY (2016)
O-GIcNAcylation in Cancer Biology: Linking Metabolism and Signaling
Christina M. Ferrer et al.
JOURNAL OF MOLECULAR BIOLOGY (2016)
Regulation of epithelial-mesenchymal transition through epigenetic and post-translational modifications
Silvia Juliana Serrano-Gomez et al.
MOLECULAR CANCER (2016)
mTORC2 Responds to Glutamine Catabolite Levels to Modulate the Hexosamine Biosynthesis Enzyme GFAT1
Joseph G. Moloughney et al.
MOLECULAR CELL (2016)
Glucose and glutamine fuel protein O-GlcNAcylation to control T cell self-renewal and malignancy
Mahima Swamy et al.
NATURE IMMUNOLOGY (2016)
Inhibition of the hexosamine biosynthetic pathway promotes castration-resistant prostate cancer
Akash K. Kaushik et al.
NATURE COMMUNICATIONS (2016)
Inhibition of O-GlcNAc transferase activity reprograms prostate cancer cell metabolism
Harri M. Itkonen et al.
ONCOTARGET (2016)
Targeting the hexosamine biosynthetic pathway and O-linked N-acetylglucosamine cycling for therapeutic and imaging capabilities in diffuse large B-cell lymphoma
Lan V. Pham et al.
ONCOTARGET (2016)
Regulatory role of hexosamine biosynthetic pathway on hepatic cancer stem cell marker CD133 under low glucose conditions
Shu-Hai Lin et al.
SCIENTIFIC REPORTS (2016)
Hijacking the Hexosamine Biosynthetic Pathway to Promote EMT-Mediated neoplastic Phenotypes
Kekoa Taparra et al.
FRONTIERS IN ONCOLOGY (2016)
Nutrient shortage triggers the hexosamine biosynthetic pathway via the GCN2-ATF4 signalling pathway
Cedric Chaveroux et al.
SCIENTIFIC REPORTS (2016)
A Small Molecule That Inhibits OGT Activity in Cells
Rodrigo F. Ortiz-Meoz et al.
ACS CHEMICAL BIOLOGY (2015)
Metabolism in embryonic and cancer stemness
Hyonchol Jang et al.
ARCHIVES OF PHARMACAL RESEARCH (2015)
A little sugar goes a long way: The cell biology of O-GlcNAc
Michelle R. Bond et al.
JOURNAL OF CELL BIOLOGY (2015)
mTOR/MYC Axis Regulates O-GlcNAc Transferase Expression and O-GlcNAcylation in Breast Cancer
Valerie L. Sodi et al.
MOLECULAR CANCER RESEARCH (2015)
Breast Tumor Heterogeneity: Source of Fitness, Hurdle for Therapy
Shany Koren et al.
MOLECULAR CELL (2015)
TET1 is a tumor suppressor of hematopoietic malignancy
Luisa Cimmino et al.
NATURE IMMUNOLOGY (2015)
Diabetes-associated dysregulation of O-GlcNAcylation in rat cardiac mitochondria
Partha S. Banerjee et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Acute loss of TET function results in aggressive myeloid cancer in mice
Jungeun An et al.
NATURE COMMUNICATIONS (2015)
Blood glucose concentration and risk of pancreatic cancer: systematic review and dose-response meta-analysis
Wei-Chih Liao et al.
BMJ-BRITISH MEDICAL JOURNAL (2015)
Blood glucose concentration and risk of pancreatic cancer: systematic review and dose-response meta-analysis
Wei-Chih Liao et al.
BMJ-BRITISH MEDICAL JOURNAL (2015)
UAP1 is overexpressed in prostate cancer and is protective against inhibitors of N-linked glycosylation
H. M. Itkonen et al.
ONCOGENE (2015)
TET2 as an epigenetic master regulator for normal and malignant hematopoiesis
Hideaki Nakajima et al.
CANCER SCIENCE (2014)
Spliced X-Box Binding Protein 1 Couples the Unfolded Protein Response to Hexosamine Biosynthetic Pathway
Zhao V. Wang et al.
CELL (2014)
Dihydropyrimidine Accumulation Is Required for the Epithelial-Mesenchymal Transition
Yoav D. Shaul et al.
CELL (2014)
TET3-OGT interaction increases the stability and the presence of OGT in chromatin
Ryo Ito et al.
GENES TO CELLS (2014)
Differential Regulation of the Ten-Eleven Translocation (TET) Family of Dioxygenases by O-Linked β-N-Acetylglucosamine Transferase (OGT)
Qiao Zhang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
Cross-talk between Two Essential Nutrient-sensitive Enzymes O-GlcNAc TRANSFERASE ( OGT) AND AMP-ACTIVATED PROTEIN KINASE ( AMPK)
John W. Bullen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
O-GlcNAcylation Regulates Cancer Metabolism and Survival Stress Signaling via Regulation of the HIF-1 Pathway
Christina M. Ferrer et al.
MOLECULAR CELL (2014)
The Ten-Eleven Translocation-2 (TET2) gene in hematopoiesis and hematopoietic diseases
E. Solary et al.
LEUKEMIA (2014)
Alteration of N-glycans and Expression of Their Related Glycogenes in the Epithelial-Mesenchymal Transition of HCV29 Bladder Epithelial Cells
Jia Guo et al.
MOLECULES (2014)
Probing the Hexosamine Biosynthetic Pathway in Human Tumor Cells by Multitargeted Tandem Mass Spectrometry
Anas M. Abdel Rahman et al.
ACS CHEMICAL BIOLOGY (2013)
O-GlcNAc Transferase Integrates Metabolic Pathways to Regulate the Stability of c-MYC in Human Prostate Cancer Cells
Harri M. Itkonen et al.
CANCER RESEARCH (2013)
AMPK Is a Negative Regulator of the Warburg Effect and Suppresses Tumor Growth In Vivo
Brandon Faubert et al.
CELL METABOLISM (2013)
TET2 and TET3 regulate GlcNAcylation and H3K4 methylation through OGT and SET1/COMPASS
Rachel Deplus et al.
EMBO JOURNAL (2013)
Ten-Eleven Translocation 1 (Tet1) Is Regulated by O-Linked N-Acetylglucosamine Transferase (Ogt) for Target Gene Repression in Mouse Embryonic Stem Cells
Feng-Tao Shi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Hyper-O-GlcNAcylation Is Anti-apoptotic and Maintains Constitutive NF-κB Activity in Pancreatic Cancer Cells
Zhiyuan Ma et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Tet Proteins Connect the O-Linked N-acetylglucosamine Transferase Ogt to Chromatin in Embryonic Stem Cells
Pietro Vella et al.
MOLECULAR CELL (2013)
TET2 promotes histone O-GlcNAcylation during gene transcription
Qiang Chen et al.
NATURE (2013)
O-GlcNAcylation-Inducing Treatments Inhibit Estrogen Receptor α Expression and Confer Resistance to 4-OH-Tamoxifen in Human Breast Cancer-Derived MCF-7 Cells
Shahzina Kanwal et al.
PLOS ONE (2013)
Strengthened glycolysis under hypoxia supports tumor symbiosis and hexosamine biosynthesis in pancreatic adenocarcinoma
Fabienne Guillaumond et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Proteomic analysis and abrogated expression of O-GlcNAcylated proteins associated with primary breast cancer
Voraratt Champattanachai et al.
PROTEOMICS (2013)
O-GlcNAcase is essential for embryonic development and maintenance of genomic stability
Yong Ryoul Yang et al.
AGING CELL (2012)
Oncogenic Kras Maintains Pancreatic Tumors through Regulation of Anabolic Glucose Metabolism
Haoqiang Ying et al.
CELL (2012)
O-GlcNAc Regulates Pluripotency and Reprogramming by Directly Acting on Core Components of the Pluripotency Network
Hyonchol Jang et al.
CELL STEM CELL (2012)
Critical Role of O-Linked β-N-Acetylglucosamine Transferase in Prostate Cancer Invasion, Angiogenesis, and Metastasis
Thomas P. Lynch et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Vertebrate protein glycosylation: diversity, synthesis and function
Kelley W. Moremen et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2012)
O-GlcNAcylation plays a role in tumor recurrence of hepatocellular carcinoma following liver transplantation
Qianqian Zhu et al.
MEDICAL ONCOLOGY (2012)
Modulators of Sensitivity and Resistance to Inhibition of PI3K Identified in a Pharmacogenomic Screen of the NCI-60 Human Tumor Cell Line Collection
Kevin A. Kwei et al.
PLOS ONE (2012)
Phosphofructokinase 1 Glycosylation Regulates Cell Growth and Metabolism
Wen Yi et al.
SCIENCE (2012)
Cancer metabolism: current perspectives and future directions
C. Munoz-Pinedo et al.
CELL DEATH & DISEASE (2012)
Cancer stem cells: an evolving concept
Long V. Nguyen et al.
NATURE REVIEWS CANCER (2012)
The dynamic stress-induced O-GlcNAc-ome highlights functions for O-GlcNAc in regulating DNA damage/repair and other cellular pathways
Natasha E. Zachara et al.
AMINO ACIDS (2011)
Protein Folding and Modification in the Mammalian Endoplasmic Reticulum
Ineke Braakman et al.
ANNUAL REVIEW OF BIOCHEMISTRY, VOL 80 (2011)
O-GlcNAcylation is a novel regulator of lung and colon cancer malignancy
Wenyi Mi et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2011)
Hallmarks of Cancer: The Next Generation
Douglas Hanahan et al.
CELL (2011)
Involvement of O-glycosylation defining oncofetal fibronectin in epithelial-mesenchymal transition process
Leonardo Freire-de-Lima et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Regulation of cancer cell metabolism
Rob A. Cairns et al.
NATURE REVIEWS CANCER (2011)
O-linked β-N-acetylglucosamine (O-GlcNAc): Extensive crosstalk with phosphorylation to regulate signaling and transcription in response to nutrients and stress
Chutikarn Butkinaree et al.
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (2010)
GlcNAcylation Plays an Essential Role in Breast Cancer Metastasis
Yuchao Gu et al.
CANCER RESEARCH (2010)
Snail1 is stabilized by O-GlcNAc modification in hyperglycaemic condition
Sang Yoon Park et al.
EMBO JOURNAL (2010)
The hexosamine biosynthetic pathway couples growth factor-induced glutamine uptake to glucose metabolism
Kathryn E. Wellen et al.
GENES & DEVELOPMENT (2010)
Simultaneous determination of nucleotide sugars with ion-pair reversed-phase HPLC
Kazuki Nakajima et al.
GLYCOBIOLOGY (2010)
O-Linked β-N-acetylglucosamine (O-GlcNAc) Regulates Stress-induced Heat Shock Protein Expression in a GSK-3β-dependent Manner
Zahra Kazemi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Cellular Metabolic Stress: Considering How Cells Respond to Nutrient Excess
Kathryn E. Wellen et al.
MOLECULAR CELL (2010)
Increased 18F-FDG uptake and expression of Glut1 in the EMT transformed breast cancer cells induced by TGF-beta
W. Li et al.
NEOPLASMA (2010)
Nutrient sensor O-GlcNAc transferase regulates breast cancer tumorigenesis through targeting of the oncogenic transcription factor FoxM1
S. A. Caldwell et al.
ONCOGENE (2010)
Up-regulation of O-GlcNAc Transferase with Glucose Deprivation in HepG2 Cells Is Mediated by Decreased Hexosamine Pathway Flux
Rodrick P. Taylor et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
An N-Glycosylation Site on the beta-Propeller Domain of the Integrin alpha 5 Subunit Plays Key Roles in Both Its Function and Site-specific Modification by beta 1,4-N-Acetylglucosaminyltransferase III
Yuya Sato et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
The basics of epithelial-mesenchymal transition
Raghu Kalluri et al.
JOURNAL OF CLINICAL INVESTIGATION (2009)
Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
Matthew G. Vander Heiden et al.
SCIENCE (2009)
Glucose deprivation stimulates O-GlcNAc modification of proteins through up-regulation of O-linked N-acetylglucosaminyltransferase
Rodrick P. Taylor et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Probing the dynamics of O-GlcNAc glycosylation in the brain using quantitative proteomics
Nelly Khidekel et al.
NATURE CHEMICAL BIOLOGY (2007)
Modification of p53 with O-linked N-acetylglucosamine regulates p53 activity and stability
Won Ho Yang et al.
NATURE CELL BIOLOGY (2006)
Mechanisms in protein O-glycan biosynthesis and clinical and molecular aspects of protein O-glycan biosynthesis defects:: A review
S Wopereis et al.
CLINICAL CHEMISTRY (2006)
The mesenchymal cell, its role in the embryo, and the remarkable signaling mechanisms that create it
ED Hay
DEVELOPMENTAL DYNAMICS (2005)
Systematic identification and molecular characterization of genes differentially expressed in breast and ovarian cancer
E Dahl et al.
JOURNAL OF PATHOLOGY (2005)
Ogt-dependent X-chromosome-linked protein glycosylation is a requisite modification in somatic cell function and embryo viability
N O'Donnell et al.
MOLECULAR AND CELLULAR BIOLOGY (2004)
Molecular physiology and pathology of the nucleotide sugar transporter family (SLC35)
N Ishida et al.
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY (2004)
Cytoplasmic O-glycosylation prevents cell surface transport of E-cadherin during apoptosis
WJ Zhu et al.
EMBO JOURNAL (2001)
Decreased UDP-GlcNAc levels abrogate proliferation control in EMeg32-deficient cells
G Boehmelt et al.
EMBO JOURNAL (2000)