期刊
BIOORGANIC CHEMISTRY
卷 87, 期 -, 页码 516-522出版社
ACADEMIC PRESS INC ELSEVIER SCIENCE
DOI: 10.1016/j.bioorg.2019.03.062
关键词
Carbonic Anhydrases (CAs); Carbonic Anhydrase Activators (CAM); Selenium; Metalloenzymes; Tellurium
A new series of beta-aminochalcogenides were designed and synthesized to identify new carbonic anhydrase activator (CAA) agents as novel tools for the management of several neurodegenerative and metabolic disorders which represent a clinical challenge without effective therapies available. Some beta-aminoselenides and beta-aminotellurides showed effective CA activating effects and a potent antioxidant activity. CAAs may have applications for memory therapy and CA deficiency syndromes.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据