期刊
AQUACULTURE RESEARCH
卷 50, 期 9, 页码 2621-2627出版社
WILEY
DOI: 10.1111/are.14218
关键词
antioxidant activity; Coriandrum sativum L; immune responses; zebrafish
类别
This study investigates the effects of Coriander (C. sativum) on the growth, antioxidant, and immune-associated genes and serum and mucosal immune parameters in zebrafish (D. rerio). The experimental fish were treated with 0 [control], 5, 10 and 20 g/kg coriander supplemented diets for 8 weeks. The results revealed that coriander remarkably increased mucosal immune parameters (the total Immunoglobulin, protease and lysozyme activity). The highest levels of the measured parameters were noticed in 20 g/kg CP treatment. Also, the zebrafish fed 20 g/kg coriander powder showed significantly higher expression gene for lysozyme and TNF-alpha. The same results were noticed in case of IL-1B gene expression. In case of sod gene expression there was no significant difference between treatments. However, regarding cat gene expression, significant difference was noticed between 20 g/kg CP treatment and other groups. In addition, no significant changes were observed between coriander fed zebrafish and control treatments regarding GH gene expression level, although IGF-I remarkable up-regulate in 20 g/kg coriander powder treatment compared other groups. In conclusion, it can be proposed that dietary Coriander powder can improve mucosal immune parameters and immune and antioxidant genes expression.
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