期刊
ANTICANCER RESEARCH
卷 39, 期 7, 页码 3379-3384出版社
INT INST ANTICANCER RESEARCH
DOI: 10.21873/anticanres.13481
关键词
PTP1B phosphatase; anticancer compounds; tyrosine phosphatase's inhibitors; review
类别
资金
- Polish Ministry of Science and Higher Education [IP2015 038774]
- Polish National Science Centre [2016/22/E/NZ4/00665]
Background/Aim: PTP1B tyrosine phosphatase is involved in the development of many types of cancers, such as breast cancer or lung cancer. Therefore, PTP1B is a promising target for anticancer therapy. The purpose of this review was to present the studies on selected PTP1B inhibitors as a possible treatment and describe the latest trends of current research in this field. Materials and Methods: This literature review was performed using the PubMed database and the analysis of previous research studies of our Department. Results: Recent studies have shown that PTP1B, due to its implication in oncogenic transformation, represents a promising drug target. Conclusion: The selected compounds that are effective PTP1B inhibitors can be considered a promising anticancer treatment, both as monotherapy and in combination with other anticancer drugs.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据