期刊
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
卷 411, 期 23, 页码 5985-5992出版社
SPRINGER HEIDELBERG
DOI: 10.1007/s00216-019-01973-1
关键词
Hydrogen sulfide; Near-infrared; Seminaphthorhodafluor dye; Bioimaging
资金
- National Natural Science Foundation of China [51603164, 21807085]
- Natural Science Foundation Research Project of Shaanxi Province [2018JQ2015]
- Scientific Research Program - Shaanxi Provincial Education Department [18JK0391]
In this study, a novel near-infrared fluorescent off-on probe for H2S based on seminaphthorhodafluor fluorophore is designed and constructed, which could be used in detection with 121-fold (23-fold) fluorescent (absorbance) enhancement at 630 nm (572 nm), fast responsiveness (completed within 5 min), high sensitivity, and lower cellular autofluorescence interference. Based on these excellent optical properties, the probe was employed to monitor H2S in red wine samples with satisfactory results. Moreover, the probe was successfully applied for monitoring and imaging H2S quantitatively in Hela cells and live athymic nude mice, indicating its potential application in biological science.
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