4.7 Review

Tandem Reactions of Ynones: via Conjugate Addition of Nitrogen-, Carbon-, Oxygen-, Boron-, Silicon-, Phosphorus-, and Sulfur-Containing Nucleophiles

期刊

ADVANCED SYNTHESIS & CATALYSIS
卷 361, 期 21, 页码 4839-4881

出版社

WILEY-V C H VERLAG GMBH
DOI: 10.1002/adsc.201900611

关键词

conjugate addition; mechanism; multifunctionality; nucleophiles; tandem reactions; ynones

资金

  1. Natural Science Foundation of Zhejiang Province [LY18B020005]

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Ynones are widely used in organic synthesis. Their great success is rooted in their multiple functional groups. This review focus on advance of ynones in published in the decade 2009-2019. Reactions triggered by the conjugate addition of nitrogen-, carbon-, oxygen-, boron-, silicon-, phosphorus-, and sulfur-containing nucleophiles are thoroughly discussed and summarized herein. Multicomponent reactions, rearrangements, cycloadditions, regio- and stereoselective synthesis, oxidations, coupling, green chemistry et al. are depicted in detail. We hope that this review will promote future research in this area.

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