Visible-Light-Promoted Oxidative Alkylarylation of N-Aryl/Benzoyl Acrylamides Through Direct C-H Bond Functionalization

Radical cascade oxidative alkylarylations of N-aryl/benzoyl acrylamides have been established through visible-light-enabled photocatalysis, furnishing a wide variety of functionalized oxindoles and isoquinolinediones in good-to-excellent yields under the synergistic interactions of an organic fluorophores-type photocatalyst 4CzIPN, trifluoroacetoxyiodobenzene (PIFA), and 1,3,5-trimethoxybenzene with visible light irradiation. The prominent features of this method are the broad substrate scope, excellent functional group tolerance, and mild reaction conditions.