期刊
ACS APPLIED MATERIALS & INTERFACES
卷 11, 期 27, 页码 24504-24511出版社
AMER CHEMICAL SOC
DOI: 10.1021/acsami.9b03522
关键词
3,4-dihydroxyphenylalanine; posttranslational modification; protein engineering; surface chemistry; universal; multifunctional protein coating; antifogging; self-cleaning; antimicrobial; biocompatibility
资金
- National Natural Science Foundation of China [21606165, 21621004, 21422605]
- Natural Science Foundation of Tianjin City [17JCQNJC05600, 18JCYBJC29500]
- Qingdao National Laboratory for Marine Science and Technology [QNLM2016ORP0407]
A multifunctional coating with antifogging, self-cleaning, and antimicrobial properties has been prepared based on a mussel-inspired chimeric protein MP-KE, which is the first example that these proteins were successfully applied to fabricate antifogging surfaces. The coating exhibits super hydrophilic properties, as indicated by contact angles less than 5 degrees and high light transmittance similar to bare glass substrates about 90%. The zwitterionic peptides of MP-KE empower water molecules to expand into thin hydrated films rapidly, providing the protein coating with diverse surface functions. Moreover, the coatings have excellent stability and a convenient preparation process because of the mussel adhesive motif of MP-KE which makes the coating anchor onto the surface strongly. As a protein material, this multifunctional coating possesses remarkable biocompatibility and has potential application prospects in the biomedical and pharmaceutical fields.
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