4.6 Article

APOE genotype and sex affect microglial interactions with plaques in Alzheimer's disease mice

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Review Neurosciences

Brain Response to Injuries: When Microglia Go Sexist

Reza Rahimian et al.

NEUROSCIENCE (2019)

Review Geriatrics & Gerontology

The Role of APOE4 in Disrupting the Homeostatic Functions of Astrocytes and Microglia in Aging and Alzheimer's Disease

Celia G. Fernandez et al.

FRONTIERS IN AGING NEUROSCIENCE (2019)

Article Immunology

Ultrastructural evidence of microglial heterogeneity in Alzheimer's disease amyloid pathology

Hassan El Hajj et al.

JOURNAL OF NEUROINFLAMMATION (2019)

Review Biochemistry & Molecular Biology

The Role of APOE and TREM2 in Alzheimers DiseaseCurrent Understanding and Perspectives

Cody M. Wolfe et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)

Article Neurosciences

Loss of TREM2 function increases amyloid seeding but reduces plaque-associated ApoE

Samira Parhizkar et al.

NATURE NEUROSCIENCE (2019)

Article Immunology

ApoE facilitates the microglial response to amyloid plaque pathology

Jason D. Ulrich et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2018)

Article Immunology

Humanized TREM2 mice reveal microglia-intrinsic and -extrinsic effects of R47H polymorphism

Wilbur M. Song et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2018)

Article Multidisciplinary Sciences

A transcriptomic atlas of aged human microglia

Marta Olah et al.

NATURE COMMUNICATIONS (2018)

Article Cell Biology

Sex-Specific Features of Microglia from Adult Mice

Alessandro Villa et al.

CELL REPORTS (2018)

Review Neurosciences

Sex and the Development of Alzheimer's Disease

Christian J. Pike

JOURNAL OF NEUROSCIENCE RESEARCH (2017)

Editorial Material Immunology

A Tale of Two Genes: Microglial Apoe and Trem2

Anna A. Pimenova et al.

IMMUNITY (2017)

Review Biochemistry & Molecular Biology

EFAD transgenic mice as a human APOE relevant preclinical model of Alzheimer's disease

Leon M. Tai et al.

JOURNAL OF LIPID RESEARCH (2017)

Article Neurosciences

Microglia limit the expansion of β-amyloid plaques in a mouse model of Alzheimer's disease

Ruohe Zhao et al.

MOLECULAR NEURODEGENERATION (2017)

Review Neurosciences

TREM2 in Neurodegenerative Diseases

Taylor R. Jay et al.

MOLECULAR NEURODEGENERATION (2017)

Article Biochemistry & Molecular Biology

TREM2 Maintains Microglial Metabolic Fitness in Alzheimer's Disease

Tyler K. Ulland et al.

Article Biochemistry & Molecular Biology

A Unique Microglia Type Associated with Restricting Development of Alzheimer's Disease

Hadas Keren-Shaul et al.

Review Endocrinology & Metabolism

Interactions between inflammation, sex steroids, and Alzheimer's disease risk factors

Mariana F. Uchoa et al.

FRONTIERS IN NEUROENDOCRINOLOGY (2016)

Article Immunology

TREM2-mediated early microglial response limits diffusion and toxicity of amyloid plaques

Yaming Wang et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2016)

Article Biochemistry & Molecular Biology

Sex differences in neurodevelopmental and neurodegenerative disorders: Focus on microglial function and neuroinflammation during development

Richa Hanamsagar et al.

JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY (2016)

Article Geriatrics & Gerontology

The APOE4 allele shows opposite sex bias in microbleeds and Alzheimer's disease of humans and mice

Mafalda Cacciottolo et al.

NEUROBIOLOGY OF AGING (2016)

Review Pathology

Emerging Concepts in Alzheimer's Disease

Harry V. Vinters

ANNUAL REVIEW OF PATHOLOGY: MECHANISMS OF DISEASE, VOL 10 (2015)

Review Neurosciences

Alzheimer's Disease Risk Genes and Mechanisms of Disease Pathogenesis

Celeste M. Karch et al.

BIOLOGICAL PSYCHIATRY (2015)

Article Biochemistry & Molecular Biology

TREM2 Lipid Sensing Sustains the Microglial Response in an Alzheimer's Disease Model

Yaming Wang et al.

Article Biochemistry & Molecular Biology

Apolipoprotein E Is a Ligand for Triggering Receptor Expressed on Myeloid Cells 2 (TREM2)

Yuka Atagi et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2015)

Article Biochemistry & Molecular Biology

The Triggering Receptor Expressed on Myeloid Cells 2 Binds Apolipoprotein E

Charles C. Bailey et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2015)

Article Medicine, Research & Experimental

TREM2 sustains microglial expansion during aging and response to demyelination

Pietro Luigi Poliani et al.

JOURNAL OF CLINICAL INVESTIGATION (2015)

Review Clinical Neurology

Neuroinflammation in Alzheimer's disease

Michael T. Heneka et al.

LANCET NEUROLOGY (2015)

Article Multidisciplinary Sciences

Microglia constitute a barrier that prevents neurotoxic protofibrillar Aβ42 hotspots around plaques

Carlo Condello et al.

NATURE COMMUNICATIONS (2015)

Article Clinical Neurology

Targeting miR-155 Restores Abnormal Microglia and Attenuates Disease in SOD1 Mice

Oleg Butovsky et al.

ANNALS OF NEUROLOGY (2015)

Article Clinical Neurology

Sex Modifies the APOE-Related Risk of Developing Alzheimer Disease

Andre Altmann et al.

ANNALS OF NEUROLOGY (2014)

Article Immunology

Human APOE4 increases microglia reactivity at Aβ plaques in a mouse model of Aβ deposition

Gustavo A. Rodriguez et al.

JOURNAL OF NEUROINFLAMMATION (2014)

Article Neurosciences

Altered microglial response to Aβ plaques in APPPS1-21 mice heterozygous for TREM2

Jason D. Ulrich et al.

MOLECULAR NEURODEGENERATION (2014)

Review Clinical Neurology

Genetics of Alzheimer's Disease

Rita Guerreiro et al.

NEUROTHERAPEUTICS (2014)

Article Neurosciences

Microglia Are Essential to Masculinization of Brain and Behavior

Kathryn M. Lenz et al.

JOURNAL OF NEUROSCIENCE (2013)

Article Neurosciences

The microglial sensome revealed by direct RNA sequencing

Suzanne E. Hickman et al.

NATURE NEUROSCIENCE (2013)

Article Medicine, General & Internal

Variant of TREM2 Associated with the Risk of Alzheimer's Disease

Thorlakur Jonsson et al.

NEW ENGLAND JOURNAL OF MEDICINE (2013)

Article Biochemistry & Molecular Biology

APOE4-specific Changes in Aβ Accumulation in a New Transgenic Mouse Model of Alzheimer Disease

Katherine L. Youmans et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2012)

Review Clinical Neurology

The role of microglia in amyloid clearance from the AD brain

C. Y. Daniel Lee et al.

JOURNAL OF NEURAL TRANSMISSION (2010)

Article Biochemistry & Molecular Biology

TREM2-and DAP12-Dependent Activation of PI3K Requires DAP10 and Is Inhibited by SHIP1

Qisheng Peng et al.

SCIENCE SIGNALING (2010)

Article Genetics & Heredity

Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease

Jean-Charles Lambert et al.

NATURE GENETICS (2009)

Article Neurosciences

Dynamics of the microglial/amyloid interaction indicate a role in plaque maintenance

Tristan Bolmont et al.

JOURNAL OF NEUROSCIENCE (2008)