相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Hybrid epithelial/mesenchymal phenotypes promote metastasis and therapy resistance across carcinomas
Mohit Kumar Jolly et al.
PHARMACOLOGY & THERAPEUTICS (2019)
Neutrophils escort circulating tumour cells to enable cell cycle progression
Barbara Maria Szczerba et al.
NATURE (2019)
Elucidating cancer metabolic plasticity by coupling gene regulation with metabolic pathways
Dongya Jia et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)
Dynamically stiffened matrix promotes malignant transformation of mammary epithelial cells via collective mechanical signaling
Matthew G. Ondeck et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)
Acquisition of a hybrid E/M state is essential for tumorigenicity of basal breast cancer cells
Cornelia Kroger et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)
Mathematical modeling of tumor-immune cell interactions
Grace E. Mahlbacher et al.
JOURNAL OF THEORETICAL BIOLOGY (2019)
Matrix stiffness mechanically conditions EMT and migratory behavior of oral squamous cell carcinoma
Bibiana F. Matte et al.
JOURNAL OF CELL SCIENCE (2019)
Non-redundant functions of EMT transcription factors
Marc P. Stemmler et al.
NATURE CELL BIOLOGY (2019)
Snail-induced claudin-11 prompts collective migration for tumour progression
Ching-Fei Li et al.
NATURE CELL BIOLOGY (2019)
Toward understanding cancer stem cell heterogeneity in the tumor microenvironment
Federico Bocci et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)
EMT Transition States during Tumor Progression and Metastasis
Ievgenia Pastushenko et al.
TRENDS IN CELL BIOLOGY (2019)
Homophilic CD44 Interactions Mediate Tumor Cell Aggregation and Polyclonal Metastasis in Patient-Derived Breast Cancer Models
Xia Liu et al.
CANCER DISCOVERY (2019)
Computational Modeling of the Crosstalk Between Macrophage Polarization and Tumor Cell Plasticity in the Tumor Microenvironment
Xuefei Li et al.
FRONTIERS IN ONCOLOGY (2019)
Stability and mean residence times for hybrid epithelial/mesenchymal phenotype
Kuheli Biswas et al.
PHYSICAL BIOLOGY (2019)
Testing the gene expression classification of the EMT spectrum
Dongya Jia et al.
PHYSICAL BIOLOGY (2019)
Deciphering the Dynamics of Epithelial-Mesenchymal Transition and Cancer Stem Cells in Tumor Progression
Federico Bocci et al.
CURRENT STEM CELL REPORTS (2019)
EMT Subtype Influences Epithelial Plasticity and Mode of Cell Migration
Nicole M. Aiello et al.
DEVELOPMENTAL CELL (2018)
Tumor Cell-Intrinsic Factors Underlie Heterogeneity of Immune Cell Infiltration and Response to Immunotherapy
Jinyang Li et al.
IMMUNITY (2018)
Modeling triple-negative breast cancer heterogeneity: Effects of stromal macrophages, fibroblasts and tumor vasculature
Kerri-Ann Norton et al.
JOURNAL OF THEORETICAL BIOLOGY (2018)
Fatty acid metabolism complements glycolysis in the selective regulatory T cell expansion during tumor growth
Ilenia Pacella et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)
Topography of epithelial-mesenchymal plasticity
Francesc Font-Clos et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)
Loss of inter-cellular cooperation by complete epithelial-mesenchymal transition supports favorable outcomes in basal breast cancer patients
Anne Grosse-Wilde et al.
Oncotarget (2018)
Prognostic impact of programmed cell death ligand 1 (PD-L1) expression and its association with epithelial-mesenchymal transition in extrahepatic cholangiocarcinoma
Takashi Ueno et al.
Oncotarget (2018)
A mechanism-based computational model to capture the interconnections among epithelial-mesenchymal transition, cancer stem cells and Notch-Jagged signaling
Federico Bocci et al.
Oncotarget (2018)
Epithelial-mesenchymal transition (EMT) signature is inversely associated with T-cell infiltration in non-small cell lung cancer (NSCLC)
Young Kwang Chae et al.
SCIENTIFIC REPORTS (2018)
Snail knockdown reverses stemness and inhibits tumour growth in ovarian cancer
N. Hojo et al.
SCIENTIFIC REPORTS (2018)
CSF-1/CSF-1R axis is associated with epithelial/mesenchymal hybrid phenotype in epithelial-like inflammatory breast cancer
Kazuharu Kai et al.
SCIENTIFIC REPORTS (2018)
Heterogeneity of Human Breast Stem and Progenitor Cells as Revealed by Transcriptional Profiling
Justin A. Colacino et al.
STEM CELL REPORTS (2018)
Combinatorial Targeting by MicroRNAs Co-ordinates Post-transcriptional Control of EMT
Joseph Cursons et al.
CELL SYSTEMS (2018)
Mathematical modeling of tumor-associated macrophage interactions with the cancer microenvironment
Grace Mahlbacher et al.
JOURNAL FOR IMMUNOTHERAPY OF CANCER (2018)
Elucidating the Metabolic Plasticity of Cancer: Mitochondrial Reprogramming and Hybrid Metabolic States
Dongya Jia et al.
CELLS (2018)
Phenotypic Plasticity, Bet-Hedging, and Androgen Independence in Prostate Cancer: Role of Non-Genetic Heterogeneity
Mohit Kumar Jolly et al.
FRONTIERS IN ONCOLOGY (2018)
Identification of the tumour transition states occurring during EMT
Ievgenia Pastushenko et al.
NATURE (2018)
TGF-β1 secreted by M2 phenotype macrophages enhances the stemness and migration of glioma cells via the SMAD2/3 signalling pathway
Zhengzheng Liu et al.
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE (2018)
Hysteresis control of epithelial-mesenchymal transition dynamics conveys a distinct program with enhanced metastatic ability
Toni Celia-Terrassa et al.
NATURE COMMUNICATIONS (2018)
The Interplay between Circulating Tumor Cells and the Immune System: From Immune Escape to Cancer Immunotherapy
Kevin Leone et al.
DIAGNOSTICS (2018)
Role of noise and parametric variation in the dynamics of gene regulatory circuits
Vivek Kohar et al.
NPJ SYSTEMS BIOLOGY AND APPLICATIONS (2018)
Epithelial-mesenchymal transition, a spectrum of states: Role in lung development, homeostasis, and disease
Mohit Kumar Jolly et al.
DEVELOPMENTAL DYNAMICS (2018)
Interconnected feedback loops among ESRP1, HAS2, and CD44 regulate epithelial-mesenchymal plasticity in cancer
Mohit Kumar Jolly et al.
APL BIOENGINEERING (2018)
CTC clusters in cancer progression and metastasis
Anna Fabisiewicz et al.
MEDICAL ONCOLOGY (2017)
ZEB1 induces LOXL2-mediated collagen stabilization and deposition in the extracellular matrix to drive lung cancer invasion and metastasis
D. H. Peng et al.
ONCOGENE (2017)
Numb prevents a complete epithelial-mesenchymal transition by modulating Notch signalling
Federico Bocci et al.
JOURNAL OF THE ROYAL SOCIETY INTERFACE (2017)
Macrophages as Key Drivers of Cancer Progression and Metastasis
Sebastian R. Nielsen et al.
MEDIATORS OF INFLAMMATION (2017)
EMT and MET: necessary or permissive for metastasis?
Mohit Kumar Jolly et al.
MOLECULAR ONCOLOGY (2017)
Epithelial/mesenchymal plasticity: how have quantitative mathematical models helped improve our understanding?
Mohit Kumar Jolly et al.
MOLECULAR ONCOLOGY (2017)
New insights into the role of EMT in tumor immune escape
Stephane Terry et al.
MOLECULAR ONCOLOGY (2017)
Multiplexed quantification of proteins and transcripts in single cells
Vanessa M. Peterson et al.
NATURE BIOTECHNOLOGY (2017)
Cell plasticity in epithelial homeostasis and tumorigenesis
Julia Varga et al.
NATURE CELL BIOLOGY (2017)
The EMT-activator Zeb1 is a key factor for cell plasticity and promotes metastasis in pancreatic cancer
Angela M. Krebs et al.
NATURE CELL BIOLOGY (2017)
Simultaneous epitope and transcriptome measurement in single cells
Marlon Stoeckius et al.
NATURE METHODS (2017)
EMT, CSCs, and drug resistance: the mechanistic link and clinical implications
Tsukasa Shibue et al.
NATURE REVIEWS CLINICAL ONCOLOGY (2017)
NOTCH SIGNALING IN DEVELOPMENT, TISSUE HOMEOSTASIS, AND DISEASE
Chris Siebel et al.
PHYSIOLOGICAL REVIEWS (2017)
Integrin-β4 identifies cancer stem cell-enriched populations of partially mesenchymal carcinoma cells
Brian Bierie et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
Epithelial-mesenchymal transition and inflammation at the site of the primary tumor
Charli Dominguez et al.
SEMINARS IN CANCER BIOLOGY (2017)
EMT cells increase breast cancer metastasis via paracrine GLI activation in neighbouring tumour cells
Deepika Neelakantan et al.
NATURE COMMUNICATIONS (2017)
Spatial computation of intratumoral T cells correlates with survival of patients with pancreatic cancer
Julienne L. Carstens et al.
NATURE COMMUNICATIONS (2017)
Characterization of epithelial-mesenchymal transition intermediate/hybrid phenotypes associated to resistance to EGFR inhibitors in non-small cell lung cancer cell lines
Valentina Fustaino et al.
ONCOTARGET (2017)
Interrogating the topological robustness of gene regulatory circuits by randomization
Bin Huang et al.
PLOS COMPUTATIONAL BIOLOGY (2017)
Pleiotropic Roles of Non-Coding RNAs in TGF-β-Mediated Epithelial-Mesenchymal Transition and Their Functions in Tumor Progression
Simon Grelet et al.
CANCERS (2017)
Stiffness-dependent motility and proliferation uncoupled by deletion of CD44
Ziba Razinia et al.
SCIENTIFIC REPORTS (2017)
Single-Cell Transcriptomic Analysis of Primary and Metastatic Tumor Ecosystems in Head and Neck Cancer
Sidharth V. Puram et al.
CELL (2017)
Survival Outcomesin Cancer Patients Predicted by a Partial EMT Gene Expression Scoring Metric
Jason T. George et al.
CANCER RESEARCH (2017)
Collective invasion in ductal and lobular breast cancer associates with distant metastasis
Antoine A. Khalil et al.
CLINICAL & EXPERIMENTAL METASTASIS (2017)
Epithelial-to-Mesenchymal Transition Contributes to Immunosuppression in Breast Carcinomas
Anushka Dongre et al.
CANCER RESEARCH (2017)
Inflammatory breast cancer: a model for investigating cluster-based dissemination
Mohit Kumar Jolly et al.
NPJ BREAST CANCER (2017)
Hybrid Cellular Metabolism Coordinated by Zic3 and Esrrb Synergistically Enhances Induction of Naive Pluripotency
Masamitsu Sone et al.
CELL METABOLISM (2017)
Modeling the Genetic Regulation of Cancer Metabolism: Interplay between Glycolysis and Oxidative Phosphorylation
Linglin Yu et al.
CANCER RESEARCH (2017)
A Patient-Derived, Pan-Cancer EMT Signature Identifies Global Molecular Alterations and Immune Target Enrichment Following Epithelial-to-Mesenchymal Transition
Milena P. Mak et al.
CLINICAL CANCER RESEARCH (2016)
Hypoxic Microenvironment Induces EMT and Upgrades Stem-Like Properties of Gastric Cancer Cells
Jinbao Guo et al.
TECHNOLOGY IN CANCER RESEARCH & TREATMENT (2016)
A Computational Model of YAP/TAZ Mechanosensing
Meng Sun et al.
BIOPHYSICAL JOURNAL (2016)
Macrophage phenotypic subtypes diametrically regulate epithelial-mesenchymal plasticity in breast cancer cells
Min Yang et al.
BMC CANCER (2016)
Hypoxia-Induced Epithelial-to-Mesenchymal Transition in Hepatocellular Carcinoma Induces an Immunosuppressive Tumor Microenvironment to Promote Metastasis
Long-Yun Ye et al.
CANCER RESEARCH (2016)
Epithelial-mesenchymal transition in tissue repair and fibrosis
Rivka C. Stone et al.
CELL AND TISSUE RESEARCH (2016)
Epithelial-Mesenchymal Transition and Immune Evasion during Lung Cancer Progression: The Chicken or the Egg?
Ila Datar et al.
CLINICAL CANCER RESEARCH (2016)
Epithelial-Mesenchymal Transition Is Associated with a Distinct Tumor Microenvironment Including Elevation of Inflammatory Signals and Multiple Immune Checkpoints in Lung Adenocarcinoma
Yanyan Lou et al.
CLINICAL CANCER RESEARCH (2016)
Numb and Numbl act to determine mammary myoepithelial cell fate, maintain epithelial identity, and support lactogenesis
Yue Zhang et al.
FASEB JOURNAL (2016)
Morphological single cell profiling of the epithelial-mesenchymal transition
Susan E. Leggett et al.
INTEGRATIVE BIOLOGY (2016)
Immunological Consequences of Epithelial-Mesenchymal Transition in Tumor Progression
Peter J. Chockley et al.
JOURNAL OF IMMUNOLOGY (2016)
Notch-Jagged signalling can give rise to clusters of cells exhibiting a hybrid epithelial/mesenchymal phenotype
Marcelo Boareto et al.
JOURNAL OF THE ROYAL SOCIETY INTERFACE (2016)
The re-polarisation of M2 and M1 macrophages and its role on cancer outcomes
Nicoline Y. den Breems et al.
JOURNAL OF THEORETICAL BIOLOGY (2016)
Atezolizumab in patients with locally advanced and metastatic urothelial carcinoma who have progressed following treatment with platinum-based chemotherapy: a single-arm, multicentre, phase 2 trial
Jonathan E. Rosenberg et al.
LANCET (2016)
Epigenetic control of adult stem cell function
Alexandra Avgustinova et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2016)
Notch signalling in context
Sarah J. Bray
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2016)
Distinct routes to metastasis: plasticity-dependent and plasticity-independent pathways
J. A. Somarelli et al.
ONCOGENE (2016)
Quantifying the landscape and kinetic paths for epithelial-mesenchymal transition from a core circuit
Chunhe Li et al.
PHYSICAL CHEMISTRY CHEMICAL PHYSICS (2016)
Immunoproteasome deficiency is a feature of non-small cell lung cancer with a mesenchymal phenotype and is associated with a poor outcome
Satyendra C. Tripathi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
Polyclonal breast cancer metastases arise from collective dissemination of keratin 14-expressing tumor cell clusters
Kevin J. Cheung et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
Intravital Correlative Microscopy: Imaging Life at the Nanoscale
Matthia A. Karreman et al.
TRENDS IN CELL BIOLOGY (2016)
Stability of the hybrid epithelial/mesenchymal phenotype
Mohit Kumar Jolly et al.
ONCOTARGET (2016)
let-7 Modulates Chromatin Configuration and Target Gene Repression through Regulation of the ARID3B Complex
Tsai-Tsen Liao et al.
CELL REPORTS (2016)
Population Heterogeneity in the Epithelial to Mesenchymal Transition Is Controlled by NFAT and Phosphorylated Sp1
Russell Gould et al.
PLOS COMPUTATIONAL BIOLOGY (2016)
Molecular Drivers of the Non-T-cell-Inflamed Tumor Microenvironment in Urothelial Bladder Cancer
Randy F. Sweis et al.
CANCER IMMUNOLOGY RESEARCH (2016)
Altered Expression and Splicing of ESRP1 in Malignant Melanoma Correlates with Epithelial-Mesenchymal Status and Tumor-Associated Immune Cytolytic Activity
Jun Yao et al.
CANCER IMMUNOLOGY RESEARCH (2016)
Phenotypic Plasticity Determines Cancer Stem Cell Therapeutic Resistance in Oral Squamous Cell Carcinoma
Adrian Biddle et al.
EBIOMEDICINE (2016)
Tumor Budding: The Name is EMT. Partial EMT.
Alexandru Dan Grigore et al.
JOURNAL OF CLINICAL MEDICINE (2016)
Claudin-low bladder tumors are immune infiltrated and actively immune suppressed
Jordan Kardos et al.
JCI INSIGHT (2016)
Epithelial-to-mesenchymal transition (EMT) induced by inflammatory priming elicits mesenchymal stromal cell-like immune-modulatory properties in cancer cells
M. Ricciardi et al.
BRITISH JOURNAL OF CANCER (2015)
Tracking and Functional Characterization of Epithelial-Mesenchymal Transition and Mesenchymal Tumor Cells during Prostate Cancer Metastasis
Marcus Ruscetti et al.
CANCER RESEARCH (2015)
Molecular Portraits of Epithelial, Mesenchymal, and Hybrid States in Lung Adenocarcinoma and Their Relevance to Survival
Mark J. Schliekelman et al.
CANCER RESEARCH (2015)
Classifying Cancers Based on T-cell Infiltration and PD-L1
Michele W. L. Teng et al.
CANCER RESEARCH (2015)
Soluble factors regulated by epithelial-mesenchymal transition mediate tumour angiogenesis and myeloid cell recruitment
Meggy Suarez-Carmona et al.
JOURNAL OF PATHOLOGY (2015)
TGF-β and EGF induced HLA-I downregulation is associated with epithelial-mesenchymal transition (EMT) through upregulation of snail in prostate cancer cells
Xiao-Hui Chen et al.
MOLECULAR IMMUNOLOGY (2015)
Epithelial-to-mesenchymal transition is dispensable for metastasis but induces chemoresistance in pancreatic cancer
Xiaofeng Zheng et al.
NATURE (2015)
Epithelial-to-mesenchymal transition is not required for lung metastasis but contributes to chemoresistance
Kari R. Fischer et al.
NATURE (2015)
Melanoma-intrinsic β-catenin signalling prevents anti-tumour immunity
Stefani Spranger et al.
NATURE (2015)
Matrix stiffness drives epithelial mesenchymal transition and tumour metastasis through a TWIST1-G3BP2 mechanotransduction pathway
Spencer C. Wei et al.
NATURE CELL BIOLOGY (2015)
A microfluidic device for label-free, physical capture of circulating tumor cell clusters
A. Fatih Sarioglu et al.
NATURE METHODS (2015)
Stemness of the hybrid Epithelial/Mesenchymal State in Breast Cancer and Its Association with Poor Survival
Anne Grosse-Wilde et al.
PLOS ONE (2015)
Jagged-Delta asymmetry in Notch signaling can give rise to a Sender/Receiver hybrid phenotype
Marcelo Boareto et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Jagged mediates differences in normal and tumor angiogenesis by affecting tip-stalk fate decision
Marcelo Boareto et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Epithelial-Mesenchymal Plasticity: A Central Regulator of Cancer Progression
Xin Ye et al.
TRENDS IN CELL BIOLOGY (2015)
Temporally sequenced anticancer drugs overcome adaptive resistance by targeting a vulnerable chemotherapy-induced phenotypic transition
Aaron Goldman et al.
NATURE COMMUNICATIONS (2015)
A role for E-cadherin in ensuring cohesive migration of a heterogeneous population of non-epithelial cells
Kyra Campbell et al.
NATURE COMMUNICATIONS (2015)
OVOL guides the epithelial-hybrid-mesenchymal transition
Dongya Jia et al.
ONCOTARGET (2015)
Coupling the modules of EMT and stemness: A tunable 'stemness window' model
Mohit Kumar Jolly et al.
ONCOTARGET (2015)
Characterization of macrophage - cancer cell crosstalk in estrogen receptor positive and triple-negative breast cancer
Maija Hollmen et al.
SCIENTIFIC REPORTS (2015)
Implications of the hybrid epithelial/mesenchymal phenotype in metastasis
Mohit Kumar Jolly et al.
FRONTIERS IN ONCOLOGY (2015)
HIF-1α Promotes Epithelial-Mesenchymal Transition and Metastasis through Direct Regulation of ZEB1 in Colorectal Cancer
Wenjing Zhang et al.
PLOS ONE (2015)
Opposite Effects of M1 and M2 Macrophage Subtypes on Lung Cancer Progression
Ang Yuan et al.
SCIENTIFIC REPORTS (2015)
Human breast cancer cells educate macrophages toward the M2 activation status
Sofia Sousa et al.
BREAST CANCER RESEARCH (2015)
Cancer-associated fibroblasts induce epithelial-mesenchymal transition of breast cancer cells through paracrine TGF-β signalling
Y. Yu et al.
BRITISH JOURNAL OF CANCER (2014)
A Positive Feedback Loop between Mesenchymal-like Cancer Cells and Macrophages Is Essential to Breast Cancer Metastasis
Shicheng Su et al.
CANCER CELL (2014)
Identification of Distinct Basal and Luminal Subtypes of Muscle-Invasive Bladder Cancer with Different Sensitivities to Frontline Chemotherapy
Woonyoung Choi et al.
CANCER CELL (2014)
A Mechanism of Hypoxia-Mediated Escape from Adaptive Immunity in Cancer Cells
Ivraym B. Barsoum et al.
CANCER RESEARCH (2014)
Circulating Tumor Cell Clusters Are Oligoclonal Precursors of Breast Cancer Metastasis
Nicola Aceto et al.
CELL (2014)
TGFβ in T cell biology and tumor immunity: Angel or devil?
Eric Tu et al.
CYTOKINE & GROWTH FACTOR REVIEWS (2014)
Epithelial-mesenchymal transition spectrum quantification and its efficacy in deciphering survival and drug responses of cancer patients
Tuan Zea Tan et al.
EMBO MOLECULAR MEDICINE (2014)
PD-L1 is a novel direct target of HIF-1α., and its blockade under hypoxia enhanced MDSC-mediated T cell activation
Muhammad Zaeem Noman et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2014)
Mathematical model of macrophage-facilitated breast cancer cells invasion
Hildur Knutsdottir et al.
JOURNAL OF THEORETICAL BIOLOGY (2014)
A mathematical model for pancreatic cancer growth and treatments
Yoram Louzoun et al.
JOURNAL OF THEORETICAL BIOLOGY (2014)
NUMB inhibition of NOTCH signalling as a therapeutic target in prostate cancer
Angela N. Flores et al.
NATURE REVIEWS UROLOGY (2014)
TGF-β-induced epithelial-to-mesenchymal transition proceeds through stepwise activation of multiple feedback loops
Jingyu Zhang et al.
SCIENCE SIGNALING (2014)
Metastasis is regulated via microRNA-200/ZEB1 axis control of tumour cell PD-L1 expression and intratumoral immunosuppression
Limo Chen et al.
NATURE COMMUNICATIONS (2014)
A high M1/M2 ratio of tumor-associated macrophages is associated with extended survival in ovarian cancer patients
Meiying Zhang et al.
JOURNAL OF OVARIAN RESEARCH (2014)
Breast Cancer Stem Cells Transition between Epithelial and Mesenchymal States Reflective of their Normal Counterparts
Suling Liu et al.
STEM CELL REPORTS (2014)
The Notch ligand Jagged1 as a target for anti-tumor therapy
Demin Li et al.
FRONTIERS IN ONCOLOGY (2014)
Tumour-infiltrating CD8+lymphocytes as an independent predictive factor for pathological complete response to primary systemic therapy in breast cancer
A. N. Seo et al.
BRITISH JOURNAL OF CANCER (2013)
LOX-Mediated Collagen Crosslinking Is Responsible for Fibrosis-Enhanced Metastasis (Publication with Expression of Concern. See vol. 79, pg. 5124, 2019)
Thomas R. Cox et al.
CANCER RESEARCH (2013)
A microRNA miR-34a-Regulated Bimodal Switch Targets Notch in Colon Cancer Stem Cells
Pengcheng Bu et al.
CELL STEM CELL (2013)
CCL2 is critical for immunosuppression to promote cancer metastasis
Chie Kudo-Saito et al.
CLINICAL & EXPERIMENTAL METASTASIS (2013)
Cutting Edge: Hypoxia-Induced Nanog Favors the Intratumoral Infiltration of Regulatory T Cells and Macrophages via Direct Regulation of TGF- β1
Meriem Hasmim et al.
JOURNAL OF IMMUNOLOGY (2013)
Innate and adaptive immune cells in the tumor microenvironment
Thomas F. Gajewski et al.
NATURE IMMUNOLOGY (2013)
The epigenetics of epithelial-mesenchymal plasticity in cancer
Wai Leong Tam et al.
NATURE MEDICINE (2013)
MicroRNA-based regulation of epithelial-hybridmesenchymal fate determination
Mingyang Lu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Circulating Breast Tumor Cells Exhibit Dynamic Changes in Epithelial and Mesenchymal Composition
Min Yu et al.
SCIENCE (2013)
An EMT spectrum defines an anoikis-resistant and spheroidogenic intermediate mesenchymal state that is sensitive to e-cadherin restoration by a src-kinase inhibitor, saracatinib (AZD0530)
R. Y-J Huang et al.
CELL DEATH & DISEASE (2013)
NF-kappa B non-cell-autonomously regulates cancer stem cell populations in the basal-like breast cancer subtype
Mizuki Yamamoto et al.
NATURE COMMUNICATIONS (2013)
Hybrid T-Helper Cells: Stabilizing the Moderate Center in a Polarized System
Sui Huang
PLOS BIOLOGY (2013)
Regulatory networks defining EMT during cancer initiation and progression
Bram De Craene et al.
NATURE REVIEWS CANCER (2013)
Dynamic equilibrium between cancer stem cells and non-stem cancer cells in human SW620 and MCF-7 cancer cell populations
G. Yang et al.
BRITISH JOURNAL OF CANCER (2012)
Accessories to the Crime: Functions of Cells Recruited to the Tumor Microenvironment
Douglas Hanahan et al.
CANCER CELL (2012)
Metastatic Colonization Requires the Repression of the Epithelial-Mesenchymal Transition Inducer Prrx1
Oscar H. Ocana et al.
CANCER CELL (2012)
Spatiotemporal Regulation of Epithelial-Mesenchymal Transition Is Essential for Squamous Cell Carcinoma Metastasis
Jeff H. Tsai et al.
CANCER CELL (2012)
Neural crest delamination and migration: From epithelium-to-mesenchyme transition to collective cell migration
Eric Theveneau et al.
DEVELOPMENTAL BIOLOGY (2012)
Epithelial-mesenchymal transition can suppress major attributes of human epithelial tumor-initiating cells
Toni Celia-Terrassa et al.
JOURNAL OF CLINICAL INVESTIGATION (2012)
Macrophage plasticity and polarization: in vivo veritas
Antonio Sica et al.
JOURNAL OF CLINICAL INVESTIGATION (2012)
A mathematical model of tumor-immune interactions
Mark Robertson-Tessi et al.
JOURNAL OF THEORETICAL BIOLOGY (2012)
Matrix rigidity regulates a switch between TGF-β1-induced apoptosis and epithelial-mesenchymal transition
Jennifer L. Leight et al.
MOLECULAR BIOLOGY OF THE CELL (2012)
Hypoxia Induces EMT in Low and Highly Aggressive Pancreatic Tumor Cells but Only Cells with Cancer Stem Cell Characteristics Acquire Pronounced Migratory Potential
Alexei V. Salnikov et al.
PLOS ONE (2012)
The Distribution of Macrophages with a M1 or M2 Phenotype in Relation to Prognosis and the Molecular Characteristics of Colorectal Cancer
Sofia Edin et al.
PLOS ONE (2012)
Selective gene-expression profiling of migratory tumor cells in vivo predicts clinical outcome in breast cancer patients
Antonia Patsialou et al.
BREAST CANCER RESEARCH (2012)
The blockade of immune checkpoints in cancer immunotherapy
Drew M. Pardoll
NATURE REVIEWS CANCER (2012)
Regulation of Epithelial-Mesenchymal Transition by Transmission of Mechanical Stress through Epithelial Tissues
Nikolce Gjorevski et al.
CANCER MICROENVIRONMENT (2012)
Endothelial Cells Create a Stem Cell Niche in Glioblastoma by Providing NOTCH Ligands That Nurture Self-Renewal of Cancer Stem-Like Cells
Thant S. Zhu et al.
CANCER RESEARCH (2011)
From Notch signaling to fine-grained patterning: Modeling meets experiments
O. Shaya et al.
CURRENT OPINION IN GENETICS & DEVELOPMENT (2011)
Notch signaling: simplicity in design, versatility in function
Emma R. Andersson et al.
DEVELOPMENT (2011)
The ZEB1/miR-200 feedback loop controls Notch signalling in cancer cells
Simone Brabletz et al.
EMBO JOURNAL (2011)
Tumor-Infiltrating CD8+ Lymphocytes Predict Clinical Outcome in Breast Cancer
Sahar M. A. Mahmoud et al.
JOURNAL OF CLINICAL ONCOLOGY (2011)
Role of YAP/TAZ in mechanotransduction
Sirio Dupont et al.
NATURE (2011)
Non-genetic heterogeneity from stochastic partitioning at cell division
Dann Huh et al.
NATURE GENETICS (2011)
TGF-β-induced IRAK-M expression in tumor-associated macrophages regulates lung tumor growth
T. J. Standiford et al.
ONCOGENE (2011)
Correction: Analysis of Epithelial and Mesenchymal Markers in Ovarian Cancer Reveals Phenotypic Heterogeneity and Plasticity
Robert Strauss et al.
PLoS One (2011)
MiR-34a Targeting of Notch Ligand Delta-Like 1 Impairs CD15+/CD133+ Tumor-Propagating Cells and Supports Neural Differentiation in Medulloblastoma
Pasqualino de Antonellis et al.
PLOS ONE (2011)
Inducible formation of breast cancer stem cells and their dynamic equilibrium with non-stem cancer cells via IL6 secretion
Dimitrios Iliopoulos et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Random partitioning of molecules at cell division
Dann Huh et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Cancer Immunoediting: Integrating Immunity's Roles in Cancer Suppression and Promotion
Robert D. Schreiber et al.
SCIENCE (2011)
A Perspective on Cancer Cell Metastasis
Christine L. Chaffer et al.
SCIENCE (2011)
Mechanical Force Affects Expression of an In Vitro Metastasis-Like Phenotype in HCT-8 Cells
Xin Tang et al.
BIOPHYSICAL JOURNAL (2010)
The M1 form of tumor-associated macrophages in non-small cell lung cancer is positively associated with survival time
Junliang Ma et al.
BMC CANCER (2010)
NOTCH Signaling Is Required for Formation and Self-Renewal of Tumor-Initiating Cells and for Repression of Secretory Cell Differentiation in Colon Cancer
Shaheen S. Sikandar et al.
CANCER RESEARCH (2010)
Antiestrogens Induce Transforming Growth Factor β-Mediated Immunosuppression in Breast Cancer
Christian M. Joffroy et al.
CANCER RESEARCH (2010)
Cancer Metastasis Is Accelerated through Immunosuppression during Snail-induced EMT of Cancer Cells
Chie Kudo-Saito et al.
CANCER CELL (2009)
Acquisition of Epithelial-Mesenchymal Transition Phenotype of Gemcitabine-Resistant Pancreatic Cancer Cells Is Linked with Activation of the Notch Signaling Pathway
Zhiwei Wang et al.
CANCER RESEARCH (2009)
TGF-β-induced epithelial to mesenchymal transition
Jian Xu et al.
CELL RESEARCH (2009)
Macrophages within NSCLC tumour islets are predominantly of a cytotoxic M1 phenotype associated with extended survival
C. M. Ohri et al.
EUROPEAN RESPIRATORY JOURNAL (2009)
Epithelial-Mesenchymal Transition Induced by Growth Suppressor p12CDK2-AP1 Promotes Tumor Cell Local Invasion but Suppresses Distant Colony Growth
Takanori Tsuji et al.
CANCER RESEARCH (2008)
The epithelial-mesenchymal transition generates cells with properties of stem cells
Sendurai A. Mani et al.
CELL (2008)
Collective epithelial migration and cell rearrangements drive mammary branching morphogenesis
Andrew J. Ewald et al.
DEVELOPMENTAL CELL (2008)
Slug is a direct Notch target required for initiation of cardiac cushion cellularization
Kyle Niessen et al.
JOURNAL OF CELL BIOLOGY (2008)
The tumor microenvironment and its role in promoting tumor growth
T. L. Whiteside
ONCOGENE (2008)
Notch signaling mediates hypoxia-induced tumor cell migration and invasion
Cecilia Sahlgren et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Adoptive cell transfer: a clinical path to effective cancer immunotherapy
Steven A. Rosenberg et al.
NATURE REVIEWS CANCER (2008)
Tumor cell apoptosis polarizes macrophages -: Role of sphingosine-1-phosphate
Andreas Weigert et al.
MOLECULAR BIOLOGY OF THE CELL (2007)
Cross-talk between paracrine-acting cytokine and chemokine pathways promotes malignancy in benign human prostatic
Mingfang Ao et al.
CANCER RESEARCH (2007)
Type, density, and location of immune cells within human colorectal tumors predict clinical outcome
Jerom Galon et al.
SCIENCE (2006)
The epithelial-mesenchymal transition: new insights in signaling, development, and disease
JM Lee et al.
JOURNAL OF CELL BIOLOGY (2006)
Opinion - The origin of the cancer stem cell: current controversies and new insights
R Bjerkvig et al.
NATURE REVIEWS CANCER (2005)
TGF-β directly targets cytotoxic T cell functions during tumor evasion of immune surveillance
DA Thomas et al.
CANCER CELL (2005)
Opinion - Migrating cancer stem cells - an integrated concept of malignant tumour progression
T Brabletz et al.
NATURE REVIEWS CANCER (2005)
The fallacy of epithelial mesenchymal transition in neoplasia
D Tarin
CANCER RESEARCH (2005)
Bacterial persistence as a phenotypic switch
NQ Balaban et al.
SCIENCE (2004)
A paracrine loop between tumor cells and macrophages is required for tumor cell migration in mammary tumors
J Wyckoff et al.
CANCER RESEARCH (2004)
Epithelial-mesenchymal transitions in tumour progression
JP Thiery
NATURE REVIEWS CANCER (2002)
Stem cells, cancer, and cancer stem cells
T Reya et al.
NATURE (2001)
分享论文
