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BIOLOGICAL PSYCHIATRY (2015)
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NEURON (2015)
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MOLECULAR BRAIN (2015)
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SCHIZOPHRENIA RESEARCH (2013)
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FASEB JOURNAL (2012)
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NATURE NEUROSCIENCE (2012)
Group II metabotropic glutamate receptor agonists and positive allosteric modulators as novel treatments for schizophrenia
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NEUROPHARMACOLOGY (2012)
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NEUROPSYCHOPHARMACOLOGY (2012)
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MOLECULAR PHARMACOLOGY (2012)
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ARCHIVES OF GENERAL PSYCHIATRY (2011)
Decoding the Signaling of a GPCR Heteromeric Complex Reveals a Unifying Mechanism of Action of Antipsychotic Drugs
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Placebo response in clinical trials with schizophrenia patients
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CURRENT OPINION IN PSYCHIATRY (2011)
Association between type-three metabotropic glutamate receptor gene (GRM3) variants and symptom presentation in treatment refractory schizophrenia
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HUMAN PSYCHOPHARMACOLOGY-CLINICAL AND EXPERIMENTAL (2011)
Targeting Group II Metabotropic Glutamate (mGlu) Receptors for the Treatment of Psychosis Associated with Alzheimer's Disease: Selective Activation of mGlu2 Receptors Amplifies β-Amyloid Toxicity in Cultured Neurons, Whereas Dual Activation of mGlu2 and mGlu3 Receptors Is Neuroprotective
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MOLECULAR PHARMACOLOGY (2011)
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Impaired Kynurenine Pathway Metabolism in The Prefrontal Cortex of Individuals With Schizophrenia
Korrapati V. Sathyasaikumar et al.
SCHIZOPHRENIA BULLETIN (2011)
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TRENDS IN MOLECULAR MEDICINE (2011)
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JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2010)
D-Aspartate activates mGlu receptors coupled to polyphosphoinositide hydrolysis in neonate rat brain slices
Gemma Molinaro et al.
NEUROSCIENCE LETTERS (2010)
Metabotropic Glutamate Receptor 5 Activation Inhibits Microglial Associated Inflammation and Neurotoxicity
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GLIA (2009)
Activation of Metabotropic Glutamate Receptor 5 Modulates Microglial Reactivity and Neurotoxicity by Inhibiting NADPH Oxidase
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JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Activation of mGlu3 Receptors Stimulates the Production of GDNF in Striatal Neurons
Giuseppe Battaglia et al.
PLOS ONE (2009)
Candidate-gene association analysis of response to risperidone in African-American and white patients with schizophrenia
B. A. Fijal et al.
PHARMACOGENOMICS JOURNAL (2009)
Mechanisms of microglia-mediated neurotoxicity in a new model of the stroke penumbra
Vikas Kaushal et al.
JOURNAL OF NEUROSCIENCE (2008)
ADX47273 [S-(4-Fluoro-phenyl)-{3-[3-(4-fluoro-phenyl)-[1,2,4]-oxadiazol-5-yl]-piperidin-1-yl}-methanone]: A Novel Metabotropic Glutamate Receptor 5-Selective Positive Allosteric Modulator with Preclinical Antipsychotic-Like and Procognitive Activities
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JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2008)
Identification of a serotonin/glutamate receptor complex implicated in psychosis
Javier Gonzalez-Maeso et al.
NATURE (2008)
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NEUROPSYCHOPHARMACOLOGY (2008)
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PSYCHIATRIC GENETICS (2008)
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PSYCHIATRIC GENETICS (2007)
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BIOLOGICAL PSYCHIATRY (2007)
Altered dimerization of metabotropic glutamate receptor 3 in schizophrenia
Corrado Corti et al.
BIOLOGICAL PSYCHIATRY (2007)
Activation of mGlu2/3 receptors as a new approach to treat schizophrenia: a randomized Phase 2 clinical trial
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NATURE MEDICINE (2007)
The use of knock-out mice unravels distinct roles for mGlu2 and mGlu3 metabotropic glutamate receptors in mechanisms of neurodegeneration/neuroprotection
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JOURNAL OF NEUROSCIENCE (2007)
Association study between kynurenine 3-monooxygenase gene and schizophrenia in the Japanese population
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GENES BRAIN AND BEHAVIOR (2006)
Association between the polymorphic GRM3 gene and negative symptom improvement during olanzapine treatment
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SCHIZOPHRENIA RESEARCH (2005)
A novel selective positive allosteric modulator of metabotropic glutamate receptor subtype 5 has in vivo activity and antipsychotic-like effects in rat behavioral models
GG Kinney et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2005)
Stimulation of microglial metabotropic glutamate receptor mGlu2 triggers tumor necrosis factor α-induced neurotoxicity in concert with microglial-derived fas ligand
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JOURNAL OF NEUROSCIENCE (2005)
No evidence for association between polymorphisms in GRM3 and schizophrenia
Nadine Norton et al.
BMC PSYCHIATRY (2005)
A case-control study of the relationship between the metabotropic glutamate receptor 3 gene and schizophrenia in the Chinese population
Q Chen et al.
SCHIZOPHRENIA RESEARCH (2005)
NMDA-induced potentiation of mGluR5 is mediated by activation of protein phosphatase 2B/calcineurin
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NEUROPHARMACOLOGY (2005)
Variation in GRM3 affects cognition, prefrontal glutamate, and risk for schizophrenia
MF Egan et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Ca2+ activity at GABAB receptors constitutively promotes metabotropic glutamate signaling in the absence of GABA
T Tabata et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Disruption of prepulse inhibition in mice lacking mGluR1
SA Brody et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2003)
Metabotropic glutamate subtype 5 receptors modulate locomotor activity and sensorimotor gating in rodents
GG Kinney et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2003)
Positive associations of polymorphisms in the metabotropic glutamate receptor type 3 gene (GRM3) with schizophrenia
Y Fujii et al.
PSYCHIATRIC GENETICS (2003)
Reactivation of ocular dominance plasticity in the adult visual cortex
T Pizzorusso et al.
SCIENCE (2002)
Activation of group II metabotropic glutamate receptors underlies microglial reactivity and neurotoxicity following stimulation with chromogranin A, a peptide up-regulated in Alzheimer's disease
DL Taylor et al.
JOURNAL OF NEUROCHEMISTRY (2002)
Metabotropic glutamate receptors 1 and 5 differentially regulate CA1 pyramidal cell function
G Mannaioni et al.
JOURNAL OF NEUROSCIENCE (2001)
The genomic organisation of the metabotropic glutamate receptor subtype 5 gene, and its association with schizophrenia
RS Devon et al.
MOLECULAR PSYCHIATRY (2001)
Activation of type 5 metabotropic glutamate receptors enhances NMDA responses in mice cortical wedges
S Attucci et al.
BRITISH JOURNAL OF PHARMACOLOGY (2001)
Metabotropic glutamate receptor 5 mediates the potentiation of N-methyl-D-aspartate responses in medium spiny striatal neurons
A Pisani et al.
NEUROSCIENCE (2001)
Serotonin model of schizophrenia: emerging role of glutamate mechanisms
GK Aghajanian et al.
BRAIN RESEARCH REVIEWS (2000)