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Abdullah Assiri et al.
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Daniel C. Payne et al.
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Benjamin Meyer et al.
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Anurodh Shankar Agrawal et al.
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Allison L. Totura et al.
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Jian Tang et al.
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Kinetics of Serologic Responses to MERS Coronavirus Infection in Humans, South Korea
Wan Beom Park et al.
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Naru Zhang et al.
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T cell-mediated immune response to respiratory coronaviruses
Rudragouda Channappanavar et al.
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Brit J. Hart et al.
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Jie Zhou et al.
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Kam-Leung Siu et al.
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Lanying Du et al.
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Yang Yang et al.
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Wei Jin et al.
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Dendritic cells: a spot on sialic acid
Helio J. Crespo et al.
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Negative regulatory approaches to the attenuation of Toll-like receptor signaling
Muhammad Ayaz Anwar et al.
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J. Brown et al.
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Fang Tang et al.
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Ye V. Liu et al.
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