4.6 Review

Linking the Endoplasmic Reticulum to Parkinson's Disease and Alpha-Synucleinopathy

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Biochemistry & Molecular Biology

Alpha-synuclein aggregates activate calcium pump SERCA leading to calcium dysregulation

Cristine Betzer et al.

EMBO REPORTS (2018)

Article Neurosciences

Toxic properties of microsome-associated alpha-synuclein species in mouse primary neurons

Emanuela Colla et al.

NEUROBIOLOGY OF DISEASE (2018)

Article Biochemistry & Molecular Biology

Alpha-synuclein induces the unfolded protein response in Parkinson's disease SNCA triplication iPSC-derived neurons

Sabrina M. Heman-Ackah et al.

HUMAN MOLECULAR GENETICS (2017)

Article Multidisciplinary Sciences

NOD1/NOD2 signaling links ER stress with inflammation

A. Marijke Keestra-Gounder et al.

NATURE (2016)

Article Biochemistry & Molecular Biology

Solid-state NMR structure of a pathogenic fibril of full-length human α-synuclein

Marcus D. Tuttle et al.

NATURE STRUCTURAL & MOLECULAR BIOLOGY (2016)

Article Multidisciplinary Sciences

α-Synuclein-induced lysosomal dysfunction occurs through disruptions in protein trafficking in human midbrain synucleinopathy models

Joseph R. Mazzulli et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)

Article Multidisciplinary Sciences

Translation from the 5′ untranslated region shapes the integrated stress response

Shelley R. Starck et al.

SCIENCE (2016)

Article Biochemistry & Molecular Biology

Solid-state NMR structure of a pathogenic fibril of full-length human α-synuclein

Marcus D. Tuttle et al.

NATURE STRUCTURAL & MOLECULAR BIOLOGY (2016)

Article Cell Biology

Regulation of Memory Formation by the Transcription Factor XBP1

Gabriela Martinez et al.

CELL REPORTS (2016)

Article Multidisciplinary Sciences

Novel mechanism of enhancing IRE1α-XBP1 signalling via the PERK-ATF4 pathway

Akio Tsuru et al.

SCIENTIFIC REPORTS (2016)

Review Biochemistry & Molecular Biology

Calcium and ROS: A mutual interplay

Agnes Goerlach et al.

REDOX BIOLOGY (2015)

Article Biochemistry & Molecular Biology

Rab11 modulates α-synuclein-mediated defects in synaptic transmission and behaviour

Carlo Breda et al.

HUMAN MOLECULAR GENETICS (2015)

Article Clinical Neurology

Direct evidence of Parkinson pathology spread from the gastrointestinal tract to the brain in rats

Staffan Holmqvist et al.

ACTA NEUROPATHOLOGICA (2014)

Article Biochemistry & Molecular Biology

α-Synuclein Multimers Cluster Synaptic Vesicles and Attenuate Recycling

Lina Wang et al.

CURRENT BIOLOGY (2014)

Article Biochemistry & Molecular Biology

Toll-like Receptor 4-mediated Endoplasmic Reticulum Stress in Intestinal Crypts Induces Necrotizing Enterocolitis*

Amin Afrazi et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2014)

Article Multidisciplinary Sciences

Control of dopaminergic neuron survival by the unfolded protein response transcription factor XBP1

Pamela Valdes et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)

Article Multidisciplinary Sciences

Intramuscular injection of α-synuclein induces CNS α-synuclein pathology and a rapid-onset motor phenotype in transgenic mice

Amanda N. Sacino et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)

Article Clinical Neurology

Transfer of human α-synuclein from the olfactory bulb to interconnected brain regions in mice

Nolwen L. Rey et al.

ACTA NEUROPATHOLOGICA (2013)

Article Clinical Neurology

Prion-like spreading of pathological α-synuclein in brain

Masami Masuda-Suzukake et al.

Article Biochemistry & Molecular Biology

Toll-like receptor-mediated IRE1α activation as a therapeutic target for inflammatory arthritis

Quan Qiu et al.

EMBO JOURNAL (2013)

Review Clinical Neurology

100 years of Lewy pathology

Michel Goedert et al.

NATURE REVIEWS NEUROLOGY (2013)

Article Behavioral Sciences

Translational control by eIF2α kinases in long-lasting synaptic plasticity and long-term memory

Mimi A. Trinh et al.

NEUROBIOLOGY OF LEARNING AND MEMORY (2013)

Review Neurosciences

The Function of α-Synuclein

Jacob T. Bendor et al.

NEURON (2013)

Article Biochemistry & Molecular Biology

The eIF2α/ATF4 pathway is essential for stress-induced autophagy gene expression

Wafa B'chir et al.

NUCLEIC ACIDS RESEARCH (2013)

Article Multidisciplinary Sciences

Negative feedback by IRE1β optimizes mucin production in goblet cells

Akio Tsuru et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)

Article Multidisciplinary Sciences

Identification and Rescue of α-Synuclein Toxicity in Parkinson Patient-Derived Neurons

Chee Yeun Chung et al.

SCIENCE (2013)

Article Biochemistry & Molecular Biology

Direct Observation of the Interconversion of Normal and Toxic Forms of α-Synuclein

Nunilo Cremades et al.

Article Medicine, Research & Experimental

Neurotoxin-Induced ER stress in mouse dopaminergic neurons involves downregulation of TRPC1 and inhibition of AKT/mTOR signaling

Senthil Selvaraj et al.

JOURNAL OF CLINICAL INVESTIGATION (2012)

Article Neurosciences

Endoplasmic Reticulum Stress Is Important for the Manifestations of α-Synucleinopathy In Vivo

Emanuela Colla et al.

JOURNAL OF NEUROSCIENCE (2012)

Article Biotechnology & Applied Microbiology

Glucose Regulated Protein 78 Diminishes α-Synuclein Neurotoxicity in a Rat Model of Parkinson Disease

Marina S. Gorbatyuk et al.

MOLECULAR THERAPY (2012)

Article Biochemistry & Molecular Biology

Parkin is transcriptionally regulated by ATF4: evidence for an interconnection between mitochondrial stress and ER stress

L. Bouman et al.

CELL DEATH AND DIFFERENTIATION (2011)

Article Biochemistry & Molecular Biology

The Endoplasmic Reticulum Stress Sensor, ATF6α, Protects against Neurotoxin-induced Dopaminergic Neuronal Death

Naohiro Egawa et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2011)

Article Biochemistry & Molecular Biology

Induction of the unfolded protein response by α-synuclein in experimental models of Parkinson's disease

Arianna Bellucci et al.

JOURNAL OF NEUROCHEMISTRY (2011)

Review Multidisciplinary Sciences

Road to Ruin: Targeting Proteins for Degradation in the Endoplasmic Reticulum

Melanie H. Smith et al.

SCIENCE (2011)

Review Multidisciplinary Sciences

The Unfolded Protein Response: From Stress Pathway to Homeostatic Regulation

Peter Walter et al.

SCIENCE (2011)

Article Multidisciplinary Sciences

α-Synuclein Promotes SNARE-Complex Assembly in Vivo and in Vitro

Jacqueline Burre et al.

SCIENCE (2010)

Article Cell Biology

Regulated Ire1-dependent decay of messenger RNAs in mammalian cells

Julie Hollien et al.

JOURNAL OF CELL BIOLOGY (2009)

Article Multidisciplinary Sciences

In vitro reconstitution of ER-stress induced ATF6 transport in COPII vesicles

Adam J. Schindler et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)

Article Multidisciplinary Sciences

The Parkinson's disease protein α-synuclein disrupts cellular Rab homeostasis

Aaron D. Gitler et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)

Article Multidisciplinary Sciences

IRE1 signaling affects cell fate during the unfolded protein response

Jonathan H. Lin et al.

SCIENCE (2007)

Article Biochemistry & Molecular Biology

XBP1 controls diverse cell type- and condition-specific transcriptional regulatory networks

Diego Acosta-Alvear et al.

MOLECULAR CELL (2007)

Article Biochemistry & Molecular Biology

ER stress triggers apoptosis by activating BH3-only protein Bim

Hamsa Puthalakath et al.

Article Biochemistry & Molecular Biology

Activation of the unfolded protein response in Parkinson's disease

J. J. M. Hoozemans et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2007)

Article Multidisciplinary Sciences

α-synuclein blocks ER-Golgi traffic and Rab1 rescues neuron loss in Parkinson's models

Antony A. Cooper et al.

SCIENCE (2006)

Article Multidisciplinary Sciences

Decay of endoplasmic reticulum-localized mRNAs during the unfolded protein response

Julie Hollien et al.

SCIENCE (2006)

Review Biochemistry & Molecular Biology

Coordination of ER and oxidative stress signaling: The PERK/Nrf2 signaling pathway

SB Cullinan et al.

INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2006)

Review Biochemistry & Molecular Biology

The endoplasmic reticulum: Folding, calcium homeostasis, signaling, and redox control

Agnes Goerlach et al.

ANTIOXIDANTS & REDOX SIGNALING (2006)

Article Multidisciplinary Sciences

On the mechanism of sensing unfolded protein in the endoplasmic reticulum

JJ Credle et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)

Article Biochemistry & Molecular Biology

Caspase-12 and caspase-4 are not required for caspase-dependent endoplasmic reticulum stress-induced apoptosis

EA Obeng et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2005)

Article Multidisciplinary Sciences

A selective inhibitor-of eIF2α dephosphorylation protects cells from ER stress

M Boyce et al.

SCIENCE (2005)

Article Biochemistry & Molecular Biology

Stable binding of ATF6 to BiP in the endoplasmic reticulum stress response

JS Shen et al.

MOLECULAR AND CELLULAR BIOLOGY (2005)

Article Multidisciplinary Sciences

Reinitiation involving upstream ORFs regulates ATF4 mRNA translation in mammalian cells

KM Vattem et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)

Article Biochemistry & Molecular Biology

Translational repression mediates activation of nuclear factor kappa B by phosphorylated translation initiation factor 2

J Deng et al.

MOLECULAR AND CELLULAR BIOLOGY (2004)

Article Biochemistry & Molecular Biology

PERK-dependent activation of Nrf2 contributes to redox homeostasis and cell survival following endoplasmic reticulum stress

SB Cullinan et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2004)

Article Cell Biology

Bax and Bak can localize to the endoplasmic reticulum to initiate apoptosis

WX Zong et al.

JOURNAL OF CELL BIOLOGY (2003)

Article Biochemistry & Molecular Biology

Dopaminergic neuronal loss and motor deficits in Caenorhabditis elegans overexpressing human α-synuclein

M Lakso et al.

JOURNAL OF NEUROCHEMISTRY (2003)

Article Biochemistry & Molecular Biology

Parkinsonian mimetics induce aspects of unfolded protein response in death of dopaminergic neurons

WA Holtz et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2003)

Review Geriatrics & Gerontology

Staging of brain pathology related to sporadic Parkinson's disease

H Braak et al.

NEUROBIOLOGY OF AGING (2003)

Article Biochemistry & Molecular Biology

XBP-1 regulates a subset of endoplasmic reticulum resident chaperone genes in the unfolded protein response

AH Lee et al.

MOLECULAR AND CELLULAR BIOLOGY (2003)

Article Biochemistry & Molecular Biology

α-synuclein, especially the Parkinson's disease-associated mutants, forms pore-like annular and tubular protofibrils

HA Lashuel et al.

JOURNAL OF MOLECULAR BIOLOGY (2002)

Article Multidisciplinary Sciences

Human α-synuclein-harboring familial Parkinson's disease-linked Ala-53→Thr mutation causes neurodegenerative disease with α-synuclein aggregation in transgenic mice

MK Lee et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)

Article Biochemistry & Molecular Biology

Translational control is required for the unfolded protein response and in vivo glucose homeostasis

D Scheuner et al.

MOLECULAR CELL (2001)

Article Medicine, Research & Experimental

Increased sensitivity to dextran sodium sulfate colitis in IRE1β-deficient mice

A Bertolotti et al.

JOURNAL OF CLINICAL INVESTIGATION (2001)

Article Biochemistry & Molecular Biology

Regulated translation initiation controls stress-induced gene expression in mammalian cells

HP Harding et al.

MOLECULAR CELL (2000)

Article Multidisciplinary Sciences

A Drosophila model of Parkinson's disease

MB Feany et al.

NATURE (2000)

Article Biochemistry & Molecular Biology

Perk is essential for translational regulation and cell survival during the unfolded protein response

HP Harding et al.

MOLECULAR CELL (2000)