Metal- and Catalyst-Free Electrochemical Synthesis of Quinazolinones from Alkenes and 2-Aminobenzamides

A metal- and catalyst-free electrochemical approach to the preparation of quinazolinones with alkenes and 2-aminobenzamides via selective anodic oxidative difunctionalization/C-C bond cleavage/cyclization/oxidation has been developed. The synthesis process features convenient operation, low cost, and environmental friendliness, which make it a promising method for the preparation of quinazolinone derivatives.