期刊
NATURE COMMUNICATIONS
卷 10, 期 -, 页码 -出版社
NATURE PUBLISHING GROUP
DOI: 10.1038/s41467-019-09851-1
关键词
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资金
- National Key R&D Project from Minister of Science and Technology, China [2016YFA0202703]
- National Natural Science Foundation of China [61875015, 31571006, 81601629, 21801019, 61501039, 11421202, 11827803]
- Beijing Natural Science Foundation [2182091]
- China Postdoctoral Science Foundation [2018M641148]
- Beijing Council of Science and Technology [Z181100004418004]
- National Youth Talent Support Program
Self-powered implantable medical electronic devices that harvest biomechanical energy from cardiac motion, respiratory movement and blood flow are part of a paradigm shift that is on the horizon. Here, we demonstrate a fully implanted symbiotic pacemaker based on an implantable triboelectric nanogenerator, which achieves energy harvesting and storage as well as cardiac pacing on a large-animal scale. The symbiotic pacemaker successfully corrects sinus arrhythmia and prevents deterioration. The open circuit voltage of an implantable triboelectric nanogenerator reaches up to 65.2 V. The energy harvested from each cardiac motion cycle is 0.495 mu J, which is higher than the required endocardial pacing threshold energy (0.377 mu J). Implantable triboelectric nanogenerators for implantable medical devices offer advantages of excellent output performance, high power density, and good durability, and are expected to find application in fields of treatment and diagnosis as in vivo symbiotic bioelectronics.
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