Complete Sequencing of Plasmids Containing blaOXA-163 and blaOXA-48 in Escherichia coli Sequence Type 131

OXA-48-like enzymes have emerged as important extended-spectrum beta -lactamases/carbapenemases in Escherichia coli sequence type 131 (ST131). We report the structures of the first fully sequenced bla(OXA-163) plasmid and of two other bla(OXA-48) plasmids in this lineage. bla(OXA-163) was located on a 71-kb IncN plasmid with other resistance genes. bla(OXA-48) was present on IncL/M plasmids, genetically similar to other bla(OXA-48) plasmid sequences, and consistent with interspecies/interlineage spread. The presence of bla(OXA-48)-like genes on epidemic plasmids in ST131 is of concern.