期刊
TRENDS IN PLANT SCIENCE
卷 24, 期 4, 页码 328-341出版社
ELSEVIER SCIENCE LONDON
DOI: 10.1016/j.tplants.2019.01.005
关键词
-
资金
- Academic Research Fund from the Ministry of Education - Singapore [MOE2015-T2-2-002]
- Singapore National Research Foundation under its Competitive Research Programme [NRF2010NRF-CRP002-018]
- National University of Singapore
- Temasek Life Sciences Laboratory
Over 160 distinct RNA modifications are known and collectively termed the epitranscriptome. Some of these modifications have been discovered in mRNA, uncovering a new layer of gene regulation. Transcriptome-wide mapping of epitranscriptomic codes and the discovery of their writers, erasers, and readers that dynamically install, remove, and interpret RNA modifications, respectively, are fundamental to understanding the epitranscriptome. Recent technologies have enabled the transcriptome-wide profiling of several mRNA modifications in Arabidopsis thaliana, providing key insights into regulating these modifications and their effects on plant development. Here we review technological innovations and recent progress in epitranscriptomics, with specific focus on N-6-methyladenosine (m(6)A), 5-methylcytosine (m(5)C), uridylation, and their roles in multiple aspects of plant development.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据