期刊
TRENDS IN IMMUNOLOGY
卷 40, 期 7, 页码 559-561出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.it.2019.05.002
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资金
- AECC Foundation
- CNIC
- Spanish Ministry of Economy, Industry. and Competitiveness (MINECO) [SAF2016-79040-R]
- Agencia Estatal de Investigacion
- FEDER (European Fund for Regional Development)
- Immunothercan-CM from Comunidad de Madrid [B2017/BMD-3733]
- FIS-Instituto de Salud Carlos III, MINECO [RD16/0015/0018-REEM]
- MINECO
- FEDER
- Foundation Acteria
- Constantes y Vitales prize (Atresmedia)
- Foundation La Marato de TV3 [201723]
- European Commission [635122-PROCROP H2020]
- European Research Council (ERC) [725091]
- Pro-CNIC Foundation
- MINECO award [SEV-2015-0505]
Type-I conventional dendritic cells (cDC1s) are key in inducing adaptive immunity. Using single-cell sequencing, Ginhoux and colleagues (Immunity 2019;50:1069-1083.e8) find that a subset of activated cDC1 s in bacteria-infected skin is critical for neutrophil recruitment via the production of VEGFa. These results reveal a crucial function for cDC1s beyond antigen presentation.
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