期刊
TETRAHEDRON LETTERS
卷 60, 期 16, 页码 1083-1090出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2019.03.043
关键词
Cyclopropane fatty acid; Total synthesis; Structural determination; Biological activity
资金
- JSPS KAKENHI [JP26282211, JP26102732, JP16K16638, JP17H02207]
Cyclopropane fatty acids (CFAs) and related compounds containing CFAs commonly occur in various natural sources, including plants or microorganisms. Some CFAs exhibit intriguing biological activities such as antifungal or immunosuppressive activities. Due to their biological importance and structural features, a number of synthetic studies have been conducted to date. These total syntheses have helped to elucidate their structural determinants or biological activities. Herein the total syntheses of naturally occurring CFAs and related compounds are summarized. (C) 2019 Elsevier Ltd. All rights reserved.
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