期刊
TETRAHEDRON
卷 75, 期 27, 页码 3697-3712出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tet.2019.05.046
关键词
Click chemistry; Azide; Alkyne; CuAAC; Cycloaddition
资金
- CAPES
- CNPq
- FAPEMIG
The current manuscript describes the catalysts in click chemistry reactions, mechanism insights and use of other metals beyond copper associated with Azide-Alkyne Cycloadditions (AAC). Due to their biological importance and several applications in various areas of science, significant efforts have been devoted to devise robust methods for the synthesis of triazoles. Among these approaches, azide-alkyne cycloadditions strategy has been consolidated as a powerful tool for preparing this class of heterocycles. Herein, click reactions involving catalysis with metals other than copper are presented and critically discussed. (C) 2019 Elsevier Ltd. All rights reserved.
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