期刊
TALANTA
卷 195, 期 -, 页码 550-557出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.talanta.2018.11.079
关键词
Sulfur-rich doped nitrogen dots; Single-source precursor; Mercury; Dual-mode sensing
资金
- National Natural Science Foundation of China [21475153, 21675178]
- Guangdong Provincial Natural Science Foundation of China [2015A030311020]
- Special Funds for Public Welfare Research and Capacity Building in Guangdong Province of China [2015A030401036]
- Guangzhou Science and Technology Program of China [201604020165]
In this work, a strategy of sulfur-rich doped nitrogen dots (S-Ndots) based on a single-source precursor (SSP) was developed and applied to sensing of Hg2+. Fluorescent S-Ndots were synthesized by microwave-assisted method using 2-azidothiazole as a single-source precursor, which served as carbon, nitrogen and sulfur source simultaneously. This SSP approach guarantee efficient core doping and improve the effect of doping in a molecular level, which is more efficient and simpler than the doping strategy with multiple precursors. The results showed that the as-synthesized S-Ndots have high sulfur component up to 24.6%, and their specific structure effectively promoted artificial peroxidase activity and coordination interaction. Interestingly, the fluorescence intensity could be quenched obviously and the peroxidase activity of the S-Ndots were selectively inhibited by Hg2+, then the S-Ndots were applied to the dual-mode sensing of Hg2+ with both fluorometric and colorimetric readout. The S-Ndots-based sensing assay with simplicity and rapidity showed high selectivity to Hg2+ with the detection limit of 0.1 mu mol/L by fluorescence spectroscopy and a distinguishable change in the color was observed by the naked eye. In addition, the accuracy and precision were evaluated based on the quantitative detection of Hg2+ in industrial waste water samples with satisfactory results. Moreover, the S-Ndots with good biocompatibility were further explored for imaging of Hg2+ in A549 cells. As a novel member of nitrogen quantum dots family, the S-Ndots hold great promise to broaden its applications in environmental and biological sensing.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据