期刊
STATISTICAL METHODS IN MEDICAL RESEARCH
卷 29, 期 2, 页码 617-635出版社
SAGE PUBLICATIONS LTD
DOI: 10.1177/0962280219837698
关键词
Measurement error; biomarkers; self-reported dietary intake data; calibration method; method of triads
类别
资金
- European Research Council grant (ERC) [647783]
- Science Foundation Ireland [SFI/12/RC/2289]
- European Research Council (ERC) [647783] Funding Source: European Research Council (ERC)
Classical approaches to assessing dietary intake are associated with measurement error. In an effort to address inherent measurement error in dietary self-reported data there is increased interest in the use of dietary biomarkers as objective measures of intake. Furthermore, there is a growing consensus of the need to combine dietary biomarker data with self-reported data. A review of state of the art techniques employed when combining biomarker and self-reported data is conducted. Two predominant methods, the calibration method and the method of triads, emerge as relevant techniques used when combining biomarker and self-reported data to account for measurement errors in dietary intake assessment. Both methods crucially assume measurement error independence. To expose and understand the performance of these methods in a range of realistic settings, their underpinning statistical concepts are unified and delineated, and thorough simulation studies are conducted. Results show that violation of the methods' assumptions negatively impacts resulting inference but that this impact is mitigated when the variation of the biomarker around the true intake is small. Thus there is much scope for the further development of biomarkers and models in tandem to achieve the ultimate goal of accurately assessing dietary intake.
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