期刊
SENSORS AND ACTUATORS B-CHEMICAL
卷 286, 期 -, 页码 148-153出版社
ELSEVIER SCIENCE SA
DOI: 10.1016/j.snb.2019.01.101
关键词
Thiophene; ESIPT; pH sensor; Mitochondria; H. pylori
资金
- Mid-Career Researcher Program [2017R1A2A1A17069537]
- National Creative Research Initiative Program [2010-0018272]
- National Research Foundation (NRF) of Korea
An hydroxythiophene-conjugated benzothiazole (T-2(OH)B) was synthesized as a pH sensitive fluorescent probe. T-2(OH)B displayed dual emission behavior due to the excited state intramolecular proton transfer (ESIPT) process, while the methoxy analogs, T-2(OMe)B, did not. T-2(OH)B showed strong fluorescence enhancement above physiological pHs. The applicability of T-2(OH)B as a biological pH indicator was demonstrated by its use for staining mitochondrial compartment and H. pylori. Owing to its strong fluorescence emission with a large stokes shift and its effective response to pH, T-2(OH)B serves as a platform for the design of new types of fluorescent probes.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据