期刊
RUSSIAN CHEMICAL BULLETIN
卷 68, 期 4, 页码 836-840出版社
SPRINGER
DOI: 10.1007/s11172-019-2493-4
关键词
Fischer indole synthesis; isocryptolepine; reduction; one-pot synthesis; indole; Cryptolepis Sanguinolenta
资金
- Russian Science Foundation [17-73-10301]
- Russian Science Foundation [17-73-10301] Funding Source: Russian Science Foundation
A novel one-pot method based on the sequence of the Fisher reaction between nitroacetophenone and phenylhydrazines, the reduction with metallic tin directly in polyphosphoric acid, and acylation has been developed for the synthesis of indoloquinolines. The obtained indolo-[3,2-c]quinolines are precursors of the analogs of isocryptolepine alkaloid.
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