期刊
PSYCHOSOMATIC MEDICINE
卷 81, 期 7, 页码 659-667出版社
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/PSY.0000000000000715
关键词
allostatic load; discrimination; dysregulation; Puerto Ricans; AL = allostatic load; BPRHS = Boston Puerto Rican Health Study; CRP = C-reactive protein; DBP = diastolic blood pressure; DHEA-S = dehydroepiandrosterone sulfate; HbA1c=glycosylated hemoglobin; HDL-C = high-density lipoprotein cholesterol; HPA = hypothalamic-pituitary-adrenal; SBP = systolic blood pressure; SES = socioeconomic status; TC = total cholesterol
资金
- National Institutes of Health-National Institute on Aging [P01-AG023394]
- United States Department of Agriculture, Agriculture Research Institute [58-1950-7-707]
- National Institutes of Health (NIH)-NHLBI Mentored Career Development Award [K01-HL120951]
- National Institute of Health [3R25CA057711]
- Cancer Disparities Research Network/Geographic Management Program (GMaP) Region 4 [3 P30 CA006927-52S2]
- CTSI Mentored Career Development Award [KL2 TR002545]
Objective Perceived discrimination is a risk factor for poor health among ethnic and racial minority groups. However, few studies have examined the association between major lifetime and everyday perceived discrimination and allostatic load (AL), a preclinical indicator of disease. We examine the association between two measures of discrimination and AL among Puerto Rican adults. Methods Using primarily wave 3 data from the longitudinal Boston Puerto Rican Health Study, we examined the association between major lifetime and everyday perceived discrimination and AL (multisystem dysregulation of 11 physiological components) among Puerto Rican adults residing in the Boston metro area (N = 882). Five models were tested using multivariable regression. The final model adjusted for demographic factors, migration factors, socioeconomic status and work history, health behaviors/risk factors, and depressive symptom. Results Respondents had a M (SD) AL score of 5.11 (1.76; range = 0-11). They had an average score of 0.21 (0.42) for major lifetime perceived discrimination (0-3) and 0.29 (0.49) for everyday perceived discrimination (0-3). In a fully adjusted model, major lifetime perceived discrimination was associated with greater AL (b = 0.56; 95% CI = 0.19 to 0.92), whereas greater everyday perceived discrimination was marginally, but not significantly, associated with lower AL (b = -0.42; 95% CI = -0.87 to 0.04). Conclusions Perceived discrimination remains a common stressor and may be a determinant of AL for Puerto Ricans, although the type of perceived discrimination may have differing effects. Further research is needed to better understand the ways in which major lifetime and everyday perceived discrimination operate to effect physiological systems among Puerto Ricans.
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