Efficient Synthesis of 2H-Indazolo[2,1-b]Phthalazine-Triones Using [PVPH]ClO4 as a Modified Polymeric Catalyst

In this work, poly(vinylpyrrolidonium) perchlorate {[PVPH]ClO4}, a newly reported modified polymeric catalyst, is used as an efficient and reusable solid acid catalyst for the promotion of the synthesis of 2H-indazolo[2,1-b]phthalazine-trione derivatives. All reactions were performed under mild conditions and the products were formed over short reaction times in excellent yields. It is important to note that this solid acid catalyst can be reused several times without any appreciable loss in its activity.

Automated summary

In this study, a newly reported modified polymeric catalyst poly(vinylpyrrolidonium) perchlorate {[PVPH]ClO4} was used as an efficient and reusable solid acid catalyst for the synthesis of 2H-indazolo[2,1-b]phthalazine-trione derivatives. The reactions were conducted under mild conditions with excellent yields obtained in short reaction times. Importantly, the solid acid catalyst demonstrated the ability to be reused multiple times without significant loss in activity.