期刊
PAKISTAN JOURNAL OF ZOOLOGY
卷 51, 期 4, 页码 1355-1361出版社
ZOOLOGICAL SOC PAKISTAN
DOI: 10.17582/journal.pjz/2019.51.4.1355.1361
关键词
Acute toxicity; Fish; Catalase; Glutathione S-transferase; Peroxidase; Superoxide dismutase; Pesticides mixture
类别
In this study insecticides toxic effects of mixture of organochlorine (endosulfan) and organophosphate (chlorpyrifos) investigated on the activity of antioxidant enzymes viz. superoxide dismutase, peroxidase, catalase and glutathione S-transferase in different organs (liver, gills, kidney, brain, heart and muscle) of fish, Labeo rohita. The LC50 of chlorpyrifos+endosulfan mixture was calculated as 1.95 +/- 0.02 mu gL(-1) for 96 h with the 95% confidence limits. The fish expose to the mixture (1: 1) for 96-h. The results obtained from this study showed that superoxide dismutase, peroxidase and glutathione S-transferase activities in the liver, gills, kidney, brain, heart and muscle were significantly (P<0.05) increased compared to control. The superoxide dismutase activity in organs of fish followed the order: liver>brain>kidney>gills>heart>muscle. The mean peroxidase activity in L. rohita followed the pattern: liver>brain>gills>kidney>heart>muscle. The glutathione S-transferse activity followed the order: brain>muscle>liver>gills>kidney>heart. However, catalase activity was significantly (P<0.05) increased in liver, gills and kidney of pesticides mixture exposed L. rohita as compared to control while it was decreased in brain, heart and muscle.
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