期刊
OTOLARYNGOLOGY-HEAD AND NECK SURGERY
卷 161, 期 2, 页码 245-250出版社
WILEY
DOI: 10.1177/0194599819838823
关键词
NCDB; SEER; cancer registry; head and neck cancer; study design; pitfalls; data analysis; editorial experiences; statistical flaws; unbalanced; errors; submission; guidelines
Objective To highlight common pitfalls observed in scientific research derived from national cancer registries, predominantly the Survival, Epidemiology, and End Results Program and the National Cancer Database. Data Sources Literature review and expert opinion. Review Methods This state-of-the-art review consolidates the literature with editorial experiences describing how and why statistically flawed studies are usually rejected for publication, highlighting common errors in submitted articles employing national cancer registries. Conclusions Pitfalls were identified in 2 major areas-design and data analysis. Design pitfalls included unbalanced cohorts, uncontrolled covariates, and flawed oncologic variables. Analytical pitfalls included incorrect application of univariate analyses, inclusion of inaccurate data, and inclusion of stage IVc disease in curative survival analysis. Additional limitations of database studies were identified, including absence of patient-related outcomes, hypothesis-generating vs practice-changing implications, and inability to differentiate between overall survival and disease-specific survival.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据