期刊
ORGANIC LETTERS
卷 21, 期 11, 页码 4137-4142出版社
AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.9b01325
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资金
- NNSFC [21390400]
- Nankai University
Cyanoalkylated diarylmethanes with biological and pharmacological potentials were synthesized from para-quinone methides and cyanoalkylating reagents through a photocatalytic process. This protocol is operationally simple and mild and has high efficiency, which gave the corresponding products in moderate to good yields. The synthetic utility of this work has been illustrated in the efficient synthesis of GPR40 agonists, which play an important role in FA-induced glucose-sensitive insulin secretion.
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