期刊
NEUROIMAGE
卷 189, 期 -, 页码 676-687出版社
ACADEMIC PRESS INC ELSEVIER SCIENCE
DOI: 10.1016/j.neuroimage.2019.02.002
关键词
-
资金
- NIH/NIGMS [T32GM007205]
Functional connectomes computed from fMRI provide a means to characterize individual differences in the patterns of BOLD synchronization across regions of the entire brain. Using four resting-state fMRI datasets with a wide range of ages, we show that individual differences of the functional connectome are stable across 3 months to 1-2 years (and even detectable at above-chance levels across 3 years). Medial frontal and frontoparietal networks appear to be both unique and stable, resulting in high ID rates, as did a combination of these two networks. We conduct analyses demonstrating that these results are not driven by head motion. We also show that edges contributing the most to a successful ID tend to connect nodes in the frontal and parietal cortices, while edges contributing the least tend to connect cross-hemispheric homologs. Our results demonstrate that the functional connectome is stable across years and that high ID rates are not an idiosyncratic aspect of a specific dataset, but rather reflect stable individual differences in the functional connectivity of the brain.
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