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Basil P. Hubbard et al.
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Alexander Panov et al.
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Gizem Donmez et al.
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E. M. C. Schrijvers et al.
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Jesse J. Smith et al.
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Krystyn Z. Bourne et al.
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K Hernández-Fonseca et al.
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JR Revollo et al.
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F Yeung et al.
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KJ Bitterman et al.
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JN Clore et al.
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G Boden et al.
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Maturation and endosomal targeting of β-site amyloid precursor protein-cleaving enzyme -: The Alzheimer's disease β-secretase
JT Huse et al.
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Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase
S Imai et al.
NATURE (2000)
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